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class=\"nx-theme-toggle\" role=\"group\" aria-label=\"Appearance of this page\" hidden><button type=\"button\" data-mode=\"light\" aria-pressed=\"false\">Light<\/button><button type=\"button\" data-mode=\"dark\" aria-pressed=\"false\">Dark<\/button><button type=\"button\" data-mode=\"auto\" aria-pressed=\"true\">Auto<\/button><\/div><div class=\"nx-folio\" aria-label=\"Document reference\"><strong>G-P13 \u00b7 INDEX \u00b7 topics<\/strong>GCRI dossier \u00b7 service level R0<\/div><div class=\"nx-hero-grid\"><div class=\"nx-hero-text\"><div class=\"nx-eyebrow-row\"><span class=\"nx-eyebrow\">GCRI<\/span><span class=\"nx-eyebrow\" aria-hidden=\"true\">\u00b7<\/span><span class=\"nx-eyebrow\">Biotechnology and Biosecurity<\/span><span class=\"nx-eyebrow\" aria-hidden=\"true\">\u00b7<\/span><span class=\"nx-eyebrow\">In development<\/span><\/div><div class=\"nx-accent-row\"><span class=\"nx-accent-rule\" aria-hidden=\"true\"><\/span><span>Biotechnology and Biosecurity \u00b7 Topics<\/span><\/div><h1 id=\"nx-title-1\" class=\"nx-hero-title\">Topics<\/h1><p class=\"nx-tagline\">Topics at Biotechnology and Biosecurity: the pages in this section are listed below, each with its own scope and status.<\/p><div class=\"nx-actions\"><a class=\"nx-btn\" data-variant=\"primary\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/synthetic-biology\/\">Open Synthetic biology <svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/a><a class=\"nx-btn\" data-variant=\"secondary\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/\">Back to Biotechnology and Biosecurity<\/a><\/div><dl class=\"nx-facts\"><div><dt class=\"nx-eyebrow\">Publisher<\/dt><dd>The Global Centre for Risk and Innovation<\/dd><\/div><div><dt class=\"nx-eyebrow\">Field<\/dt><dd>Health and biosecurity, Food and agriculture<\/dd><\/div><div><dt class=\"nx-eyebrow\">Status<\/dt><dd>In development<\/dd><\/div><div><dt class=\"nx-eyebrow\">Service level<\/dt><dd>R0: information and enquiries<\/dd><\/div><\/dl><\/div><\/div><\/div><\/section> <nav class=\"nx-index-strip\" data-nx-spy=\"true\" aria-label=\"On this page\"><div class=\"nx-container\"><a href=\"#nx-sec-brief-answer\"><span>01<\/span>The short answer<\/a><a href=\"#nx-sec-about-this-section\"><span>02<\/span>Topics at Biotechnology and\u2026<\/a><a href=\"#nx-sec-pg-map-of-topics\"><span>03<\/span>How the biosecurity topics connect<\/a><a href=\"#nx-sec-terms\"><span>04<\/span>Terms used on this page<\/a><a href=\"#nx-sec-pg-sources\"><span>05<\/span>Where this page's references lead<\/a><a href=\"#nx-s-7-sec\"><span>06<\/span>Pages in Topics<\/a><\/div><\/nav> <section id=\"nx-sec-brief-answer\" class=\"nx-section\" data-hue=\"health\" aria-labelledby=\"nx-s-2\"><div class=\"nx-container\"><div class=\"nx-section-head\"><div class=\"nx-eyebrow-row\"><span class=\"nx-eyebrow\">01<\/span><span class=\"nx-rule\" aria-hidden=\"true\"><\/span><span class=\"nx-eyebrow\">In brief<\/span><\/div><h2 id=\"nx-s-2\" class=\"nx-section-title\">The short answer.<\/h2><p class=\"nx-lede\">The Biotechnology and Biosecurity topics are the eight subject dossiers of its field, among them synthetic biology, biomanufacturing, and diagnostics and therapeutics. Each dossier sets out how the risk develops, what is measured and in which units, the public sources and their licences, the methods, who decides and the limits of the evidence.<\/p><\/div><\/div><\/section><section id=\"nx-sec-about-this-section\" class=\"nx-section\" data-hue=\"food\" data-tone=\"alt\" data-variant=\"inset\" aria-labelledby=\"nx-s-3\"><div class=\"nx-container\"><div class=\"nx-section-head\"><div class=\"nx-eyebrow-row\"><span class=\"nx-eyebrow\">02<\/span><span class=\"nx-rule\" aria-hidden=\"true\"><\/span><span class=\"nx-eyebrow\">About this section<\/span><\/div><h2 id=\"nx-s-3\" class=\"nx-section-title\">Topics at Biotechnology and Biosecurity.<\/h2><p class=\"nx-lede\">GCRI is a research, development and policy institution. It is not a regulator, and it does not certify, license or approve; its findings carry their methods and uncertainty.<\/p><\/div><\/div><\/section><section id=\"nx-sec-pg-map-of-topics\" class=\"nx-section\" data-hue=\"health\" data-variant=\"stack\" aria-labelledby=\"nx-s-4\"><div class=\"nx-container\"><div class=\"nx-section-head\"><div class=\"nx-eyebrow-row\"><span class=\"nx-eyebrow\">03<\/span><span class=\"nx-rule\" aria-hidden=\"true\"><\/span><span class=\"nx-eyebrow\">How the topics fit<\/span><\/div><h2 id=\"nx-s-4\" class=\"nx-section-title\">How the biosecurity topics connect.<\/h2><\/div><div class=\"nx-section-body\"><p class=\"nx-p\">The topics on this platform are framed for regulators, biosafety professionals and preparedness planners, at capacity and oversight level only. They concern how institutions review research with misuse potential, how laboratory and countermeasure capacity is assessed, and how human, animal and plant health preparedness connect. A reader looks for governance evidence; no topic gives technical biological detail. Methods come from <a class=\"nx-link\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/stem\/epidemiology\/\">epidemiology<\/a> and process safety.<\/p><p class=\"nx-p\">The topics on this platform are framed at capacity and oversight level.<\/p><\/div><\/div><\/section><section id=\"nx-sec-terms\" class=\"nx-section\" data-hue=\"food\" data-tone=\"alt\" aria-labelledby=\"nx-s-5\"><div class=\"nx-container\"><div class=\"nx-section-head\"><div class=\"nx-eyebrow-row\"><span class=\"nx-eyebrow\">04<\/span><span class=\"nx-rule\" aria-hidden=\"true\"><\/span><span class=\"nx-eyebrow\">Key terms<\/span><\/div><h2 id=\"nx-s-5\" class=\"nx-section-title\">Terms used on this page.<\/h2><p class=\"nx-lede\">Each term as this page uses it. Where a standard-setting body defines the term, the wording follows that body.<\/p><\/div><div class=\"nx-section-body\"><div class=\"nx-table-wrap\"><table class=\"nx-table\" data-stack=\"true\"><thead><tr><th scope=\"col\">Term<\/th><th scope=\"col\">Definition<\/th><\/tr><\/thead><tbody><tr><td data-label=\"Term\">Biosafety<\/td><td data-label=\"Definition\">Measures that assess and manage risks to health and the environment from living modified organisms, governed internationally by the Cartagena Protocol.<\/td><\/tr><tr><td data-label=\"Term\">Biosecurity<\/td><td data-label=\"Definition\">Measures that prevent the loss, theft, misuse or deliberate release of pathogens and toxins.<\/td><\/tr><tr><td data-label=\"Term\">Dual-use research of concern<\/td><td data-label=\"Definition\">Life sciences research that could be directly misapplied to threaten health, agriculture, the environment or security.<\/td><\/tr><tr><td data-label=\"Term\">One Health<\/td><td data-label=\"Definition\">An integrated approach that aims to balance and optimise the health of people, animals and ecosystems, as the Quadripartite organizations define it.<\/td><\/tr><tr><td data-label=\"Term\">Living modified organism<\/td><td data-label=\"Definition\">An organism with a novel combination of genetic material obtained through modern biotechnology, as the Cartagena Protocol defines it.<\/td><\/tr><\/tbody><\/table><\/div><\/div><\/div><\/section><section id=\"nx-sec-pg-sources\" class=\"nx-section\" data-hue=\"health\" data-variant=\"inset\" aria-labelledby=\"nx-s-6\"><div class=\"nx-container\"><div class=\"nx-section-head\"><div class=\"nx-eyebrow-row\"><span class=\"nx-eyebrow\">05<\/span><span class=\"nx-rule\" aria-hidden=\"true\"><\/span><span class=\"nx-eyebrow\">Sources<\/span><\/div><h2 id=\"nx-s-6\" class=\"nx-section-title\">Where this page's references lead.<\/h2><p class=\"nx-lede\">The bodies and documents this page is read against. Status and editions change; each link goes to the issuing body.<\/p><\/div><div class=\"nx-section-body\"><ul class=\"nx-list\" data-nav=\"true\"><li><a class=\"nx-link\" href=\"https:\/\/www.who.int\/publications\/i\/item\/9789240056107\" target=\"_blank\" rel=\"noopener\"><span>WHO Global guidance framework for the responsible use of the life sciences<\/span><svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/a><\/li><li><a class=\"nx-link\" href=\"https:\/\/www.who.int\/publications\/i\/item\/9789240011311\" target=\"_blank\" rel=\"noopener\"><span>WHO Laboratory Biosafety Manual, fourth edition<\/span><svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/a><\/li><li><a class=\"nx-link\" href=\"https:\/\/disarmament.unoda.org\/biological-weapons\/\" target=\"_blank\" rel=\"noopener\"><span>Biological Weapons Convention (UNODA)<\/span><svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/a><\/li><li><a class=\"nx-link\" href=\"https:\/\/www.iso.org\/standard\/71293.html\" target=\"_blank\" rel=\"noopener\"><span>ISO 35001:2019 Biorisk management for laboratories (ISO)<\/span><svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/a><\/li><\/ul><\/div><\/div><\/section><section id=\"nx-s-7-sec\" class=\"nx-section\" data-hue=\"food\" data-tone=\"alt\" aria-labelledby=\"nx-s-7\"><div class=\"nx-container\"><div class=\"nx-section-head\"><div class=\"nx-eyebrow-row\"><span class=\"nx-eyebrow\">06<\/span><span class=\"nx-rule\" aria-hidden=\"true\"><\/span><span class=\"nx-eyebrow\">Pages<\/span><\/div><h2 id=\"nx-s-7\" class=\"nx-section-title\">Pages in Topics.<\/h2><\/div><div class=\"nx-section-body\"><div class=\"nx-cards\" data-cols=\"3\"><a class=\"nx-card\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/synthetic-biology\/\"><span class=\"nx-eyebrow\">Topic<\/span><h3 class=\"nx-h4 nx-mt-2\">Synthetic biology<\/h3><p class=\"nx-p nx-mt-1\">Design-build-test biology and safeguards.<\/p><\/a><a class=\"nx-card\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/biomanufacturing\/\"><span class=\"nx-eyebrow\">Topic<\/span><h3 class=\"nx-h4 nx-mt-2\">Biomanufacturing<\/h3><p class=\"nx-p nx-mt-1\">Industrial biology and production systems.<\/p><\/a><a class=\"nx-card\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/diagnostics-and-therapeutics\/\"><span class=\"nx-eyebrow\">Topic<\/span><h3 class=\"nx-h4 nx-mt-2\">Diagnostics and therapeutics<\/h3><p class=\"nx-p nx-mt-1\">Health innovation and evaluation.<\/p><\/a><a class=\"nx-card\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/agricultural-biotechnology\/\"><span class=\"nx-eyebrow\">Topic<\/span><h3 class=\"nx-h4 nx-mt-2\">Agricultural biotechnology<\/h3><p class=\"nx-p nx-mt-1\">Food system applications and environmental effects.<\/p><\/a><a class=\"nx-card\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/biological-threats\/\"><span class=\"nx-eyebrow\">Topic<\/span><h3 class=\"nx-h4 nx-mt-2\">Biological threats<\/h3><p class=\"nx-p nx-mt-1\">Accidental, natural and deliberate biological risks.<\/p><\/a><a class=\"nx-card\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/lab-biosafety-and-biosecurity\/\"><span class=\"nx-eyebrow\">Topic<\/span><h3 class=\"nx-h4 nx-mt-2\">Lab biosafety and biosecurity<\/h3><p class=\"nx-p nx-mt-1\">Research environment controls and governance.<\/p><\/a><a class=\"nx-card\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/one-health-impacts\/\"><span class=\"nx-eyebrow\">Topic<\/span><h3 class=\"nx-h4 nx-mt-2\">One health impacts<\/h3><p class=\"nx-p nx-mt-1\">Cross-species and environmental factors.<\/p><\/a><a class=\"nx-card\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/dual-use-and-ethics\/\"><span class=\"nx-eyebrow\">Topic<\/span><h3 class=\"nx-h4 nx-mt-2\">Dual use and ethics<\/h3><p class=\"nx-p nx-mt-1\">Responsible research and escalation.<\/p><\/a><\/div><\/div><\/div><\/section><section class=\"nx-section\" data-tone=\"alt\" aria-labelledby=\"nx-rel-8\"><div class=\"nx-container\"><span class=\"nx-eyebrow\">Related<\/span><h2 id=\"nx-rel-8\" class=\"nx-h3 nx-mt-2\">Around Biotechnology and Biosecurity.<\/h2><nav class=\"nx-related nx-mt-3\" aria-label=\"Related\"><a href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/about\/\">Mandate and publisher <svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/a><a href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/field\/\">Field overview <svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/a><a href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/research\/\">Research and evidence <svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M3 8h10M9 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An enquiry receives a reference and names the next step; applications, payments, compute allocations and registrations open only when their team, terms and review capacity exist.<\/p><div class=\"nx-actions\"><a class=\"nx-btn\" data-variant=\"primary\" href=\"mailto:contact@therisk.global?subject=Biotechnology%20and%20Biosecurity%3A%20Topics\">Write to the team <svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.5\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/a><a class=\"nx-btn\" data-variant=\"secondary\" href=\"https:\/\/therisk.global\/biotechnology-biosecurity\/contact\/\">See all contact routes<\/a><\/div><\/div><\/section><\/div><\/div><script class=\"_iub_cs_skip\">window.__nxMount ? window.__nxMount(document.currentScript) : null;<\/script>\n\n\n<script type=\"application\/ld+json\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"DefinedTermSet\",\"@id\":\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/#terms\",\"name\":\"Key terms: Topics\",\"inLanguage\":\"en\",\"isPartOf\":{\"@id\":\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/#webpage\"},\"hasDefinedTerm\":[{\"@type\":\"DefinedTerm\",\"name\":\"Biosafety\",\"description\":\"Measures that assess and manage risks to health and the environment from living modified organisms, governed internationally by the Cartagena Protocol.\",\"inDefinedTermSet\":{\"@id\":\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/#terms\"}},{\"@type\":\"DefinedTerm\",\"name\":\"Biosecurity\",\"description\":\"Measures that prevent the loss, theft, misuse or deliberate release of pathogens and toxins.\",\"inDefinedTermSet\":{\"@id\":\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/#terms\"}},{\"@type\":\"DefinedTerm\",\"name\":\"Dual-use research of concern\",\"description\":\"Life sciences research that could be directly misapplied to threaten health, agriculture, the environment or security.\",\"inDefinedTermSet\":{\"@id\":\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/#terms\"}},{\"@type\":\"DefinedTerm\",\"name\":\"One Health\",\"description\":\"An integrated approach that aims to balance and optimise the health of people, animals and ecosystems, as the Quadripartite organizations define it.\",\"inDefinedTermSet\":{\"@id\":\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/#terms\"}},{\"@type\":\"DefinedTerm\",\"name\":\"Living modified organism\",\"description\":\"An organism with a novel combination of genetic material obtained through modern biotechnology, as the Cartagena Protocol defines it.\",\"inDefinedTermSet\":{\"@id\":\"https:\/\/therisk.global\/biotechnology-biosecurity\/topics\/#terms\"}}]}]}<\/script>\n\n<!-- nx-rev:c4b4f31f5c8fce66 -->","protected":false},"excerpt":{"rendered":"<p>LightDarkAuto G-P13 \u00b7 INDEX \u00b7 topicsGCRI dossier \u00b7 service level R0 GCRI\u00b7Biotechnology and Biosecurity\u00b7In development Biotechnology and Biosecurity \u00b7 Topics Topics Topics at Biotechnology and Biosecurity: the pages in this &hellip; 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