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\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\"><style>#nxe-nr-gcri-editions-gs-15-coupled-system.nxe{display:block;box-sizing:border-box;max-width:1180px;margin:0 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8px;text-align:left;vertical-align:top;border-bottom:1px solid;border-color:inherit}#nxe-nr-gcri-editions-gs-15-coupled-system.nxe svg{display:none}#nxe-nr-gcri-editions-gs-15-coupled-system.nxe svg.nx-i{display:inline-block;width:18px;height:18px;vertical-align:-3px}#nxe-nr-gcri-editions-gs-15-coupled-system.nxe :where([role=\"tablist\"],[role=\"toolbar\"],[hidden],button,.nx-theme-toggle,.nx-live-slot){display:none}#nxe-nr-gcri-editions-gs-15-coupled-system.nxe img{max-width:100%;height:auto}<\/style><svg class=\"nx-defs\" aria-hidden=\"true\" focusable=\"false\" width=\"0\" height=\"0\"><defs><linearGradient id=\"nx-gi\" x1=\"0\" y1=\"0\" x2=\"1\" y2=\"1\"><stop offset=\"0\" class=\"nx-gi-a\"\/><stop offset=\"0.55\" class=\"nx-gi-b\"\/><stop offset=\"1\" class=\"nx-gi-c\"\/><\/linearGradient><linearGradient id=\"nx-giu\" gradientUnits=\"userSpaceOnUse\" x1=\"0\" y1=\"0\" x2=\"800\" y2=\"0\"><stop offset=\"0\" class=\"nx-gi-a\"\/><stop offset=\"0.55\" class=\"nx-gi-b\"\/><stop offset=\"1\" class=\"nx-gi-c\"\/><\/linearGradient><linearGradient id=\"nx-gp\" x1=\"0\" y1=\"0\" x2=\"1\" y2=\"1\"><stop offset=\"0\" class=\"nx-gp-a\"\/><stop offset=\"1\" class=\"nx-gp-b\"\/><\/linearGradient><\/defs><\/svg><div class=\"nrp\"><div class=\"nrp-wrap\"><p class=\"nrj-draft\" data-nrj-shared=\"draft\" role=\"note\"><strong>Draft, not yet released.<\/strong> In stewardship review. Not indexed until the first approved release.<\/p><div class=\"nrp-reader\"><nav class=\"nrp-rail\" aria-label=\"Contents of Global Science and Engineering Frontier 2026\"><p class=\"nf-ui-eyebrow\">Contents<\/p><ol class=\"nrp-toc\"><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Edition home<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/summary\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Executive summary<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/coupled-system\/\" aria-current=\"page\"><span class=\"nrp-toc-n\">1<\/span><span>Science is where the frontier is made<\/span><\/a><ol class=\"nrp-toc-sub\"><li><a href=\"#nx-nrp-gs-15-c1-s1\">1.1 The questions this part answers<\/a><\/li><li><a href=\"#nx-nrp-gs-15-c1-s2\">1.2 The argument<\/a><\/li><li><a href=\"#nx-nrp-gs-15-c1-s3\">1.3 Twenty couplings between five systems<\/a><\/li><li><a href=\"#nx-nrp-gs-15-c1-s4\">1.4 Reinforcing loops<\/a><\/li><\/ol><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/findings\/\"><span class=\"nrp-toc-n\">2<\/span><span>Key findings<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/systems-and-sectors\/\"><span class=\"nrp-toc-n\">3<\/span><span>Systems and sectors at baseline<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/risk-and-capability\/\"><span class=\"nrp-toc-n\">4<\/span><span>Risks and capability<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/scenario\/\"><span class=\"nrp-toc-n\">5<\/span><span>Loss of trust in the research record during a fast-moving emergency<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/lenses-and-readings\/\"><span class=\"nrp-toc-n\">6<\/span><span>Readings from the other desks<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/agenda\/\"><span class=\"nrp-toc-n\">7<\/span><span>The 2027 agenda<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/systems-in-depth\/\"><span class=\"nrp-toc-n\">8<\/span><span>Systems in depth<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/methodology\/\"><span class=\"nrp-toc-n\">A<\/span><span>Methodology<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/data\/\"><span class=\"nrp-toc-n\">B<\/span><span>Data appendix<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/references\/\"><span class=\"nrp-toc-n\">C<\/span><span>References and record<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/full\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Complete edition, for print<\/span><\/a><\/li><\/ol><div class=\"nrp-actions\"><a class=\"nf-ui-btn\" data-variant=\"secondary\" href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/full\/\"><svg class=\"nrp-i\" viewBox=\"0 0 24 24\" aria-hidden=\"true\" focusable=\"false\"><path d=\"M6 18H4a2 2 0 0 1-2-2v-5a2 2 0 0 1 2-2h16a2 2 0 0 1 2 2v5a2 2 0 0 1-2 2h-2\"\/><path d=\"M6 9V3a1 1 0 0 1 1-1h10a1 1 0 0 1 1 1v6\"\/><rect x=\"6\" y=\"14\" width=\"12\" height=\"8\" rx=\"1\"\/><\/svg>Print or save as PDF<\/a><\/div><\/nav><article class=\"nrp-flow\" aria-labelledby=\"nx-nrp-gs-15-c1-top\"><header class=\"nrp-chap-head\" id=\"nx-nrp-gs-15-c1-top\"><ul class=\"nrp-eyerow\"><li class=\"nf-ui-eyebrow\"><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/\">Global Science and Engineering Frontier 2026<\/a><\/li><li class=\"nf-ui-eyebrow\">Chapter 1<\/li><\/ul><span class=\"nrp-rule\" aria-hidden=\"true\"><\/span><h1 class=\"pp-hero-title\">Science is where the frontier is made<\/h1><p class=\"nrp-lede\">Part I describes systems and their couplings. It ranks no country or operator and assesses no authority.<\/p><p class=\"nrp-chap-meta\"><span>7 min read<\/span><span>2 figures<\/span><span>2 tables<\/span><span>17 notes<\/span><span>NR-SECTOR-SCIENCE-GLOBAL-2026-BASELINE<\/span><\/p><details class=\"nrp-toc-m\"><summary>Contents<\/summary><ol class=\"nrp-toc\"><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Edition home<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/summary\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Executive summary<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/coupled-system\/\" aria-current=\"page\"><span class=\"nrp-toc-n\">1<\/span><span>Science is where the frontier is made<\/span><\/a><ol class=\"nrp-toc-sub\"><li><a href=\"#nx-nrp-gs-15-c1-s1\">1.1 The questions this part answers<\/a><\/li><li><a href=\"#nx-nrp-gs-15-c1-s2\">1.2 The argument<\/a><\/li><li><a href=\"#nx-nrp-gs-15-c1-s3\">1.3 Twenty couplings between five systems<\/a><\/li><li><a href=\"#nx-nrp-gs-15-c1-s4\">1.4 Reinforcing loops<\/a><\/li><\/ol><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/findings\/\"><span class=\"nrp-toc-n\">2<\/span><span>Key findings<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/systems-and-sectors\/\"><span class=\"nrp-toc-n\">3<\/span><span>Systems and sectors at baseline<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/risk-and-capability\/\"><span class=\"nrp-toc-n\">4<\/span><span>Risks and capability<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/scenario\/\"><span class=\"nrp-toc-n\">5<\/span><span>Loss of trust in the research record during a fast-moving emergency<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/lenses-and-readings\/\"><span class=\"nrp-toc-n\">6<\/span><span>Readings from the other desks<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/agenda\/\"><span class=\"nrp-toc-n\">7<\/span><span>The 2027 agenda<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/systems-in-depth\/\"><span class=\"nrp-toc-n\">8<\/span><span>Systems in depth<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/methodology\/\"><span class=\"nrp-toc-n\">A<\/span><span>Methodology<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/data\/\"><span class=\"nrp-toc-n\">B<\/span><span>Data appendix<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/references\/\"><span class=\"nrp-toc-n\">C<\/span><span>References and record<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/full\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Complete edition, for print<\/span><\/a><\/li><\/ol><\/details><\/header><section class=\"nrp-block\" id=\"nx-nrp-gs-15-c1-s1\" aria-labelledby=\"nx-nrp-gs-15-c1-s1-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-gs-15-c1-s1-h\"><span class=\"nrp-num\">1.1<\/span><span>The questions this part answers<\/span><\/h2><h3 class=\"nrp-h3\">Key questions<\/h3><ul class=\"nrp-list\"><li>Where is science and engineering risk concentrated?<\/li><li>Which couplings carry science and engineering shocks into other <a class=\"nx-link nx-term\" href=\"https:\/\/docs.therisk.global\/organization\/systems\" data-tc=\"Systems\" data-tk=\"Nexus Standards\" data-td=\"The twenty Nexus systems, NXS-CMD to NXS-LAB\">systems<\/a>?<\/li><li>Which science and engineering capabilities hold under compound stress?<\/li><li>What must 2027 evidence measure first?<\/li><\/ul><h3 class=\"nrp-h3\">In this part<\/h3><ul class=\"nrp-chips\"><li class=\"nf-ui-chip\">Narrative<\/li><li class=\"nf-ui-chip\">Headline finding<\/li><li class=\"nf-ui-chip\">Lead figure<\/li><li class=\"nf-ui-chip\">Five coupling chapters<\/li><li class=\"nf-ui-chip\">Twelve-domain reading<\/li><li class=\"nf-ui-chip\">Sector screens<\/li><li class=\"nf-ui-chip\">Dependency matrix<\/li><li class=\"nf-ui-chip\">Risk objects<\/li><li class=\"nf-ui-chip\">Capability ladder<\/li><li class=\"nf-ui-chip\">Scenario<\/li><li class=\"nf-ui-chip\">Three lenses<\/li><li class=\"nf-ui-chip\">Portfolio<\/li><\/ul><\/section><section class=\"nrp-block\" id=\"nx-nrp-gs-15-c1-s2\" aria-labelledby=\"nx-nrp-gs-15-c1-s2-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-gs-15-c1-s2-h\"><span class=\"nrp-num\">1.2<\/span><span>The argument<\/span><\/h2><div class=\"nrp-prose\"><p>Science is usually reported as a series of results. The 2026 evidence reads it as a system with funders, people, instruments, journals and data that other <a class=\"nx-link nx-term\" href=\"https:\/\/docs.therisk.global\/organization\/systems\" data-tc=\"Systems\" data-tk=\"Nexus Standards\" data-td=\"The twenty Nexus systems, NXS-CMD to NXS-LAB\">systems<\/a> depend on. Medicines, forecasts, chips and models all start in it<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n11\" id=\"nx-nrp-gs-15-c1-r11\" aria-label=\"Note 11\">11<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n17\" id=\"nx-nrp-gs-15-c1-r17\" aria-label=\"Note 17\">17<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n9\" id=\"nx-nrp-gs-15-c1-r9\" aria-label=\"Note 9\">9<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n4\" id=\"nx-nrp-gs-15-c1-r4\" aria-label=\"Note 4\">4<\/a><\/sup>.<\/p><p>The system is large and uneven. Worldwide spending reached USD 3.48 trillion in 2024, with China and the United States together performing more than half of it<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n1\" id=\"nx-nrp-gs-15-c1-r1\" aria-label=\"Note 1\">1<\/a><\/sup>. Researcher density runs from 88 per million in Sub-Saharan Africa to 5,006 in Northern America<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n2\" id=\"nx-nrp-gs-15-c1-r2\" aria-label=\"Note 2\">2<\/a><\/sup>.<\/p><p>The record is growing faster than it can be checked. Articles, preprints and AI-assisted outputs rise each year<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n1\" aria-label=\"Note 1\">1<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n5\" id=\"nx-nrp-gs-15-c1-r5\" aria-label=\"Note 5\">5<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n9\" aria-label=\"Note 9\">9<\/a><\/sup>, and retraction notices peaked at 15,582 in 2023<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n6\" id=\"nx-nrp-gs-15-c1-r6\" aria-label=\"Note 6\">6<\/a><\/sup>. Case studies show that coordinated fraud is large, resilient and growing<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n14\" id=\"nx-nrp-gs-15-c1-r14\" aria-label=\"Note 14\">14<\/a><\/sup>, and a replication project in psychology found 36% of replications significant against 97% of originals<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n16\" id=\"nx-nrp-gs-15-c1-r16\" aria-label=\"Note 16\">16<\/a><\/sup>.<\/p><p>The frontier is becoming more computational. Five exascale systems now sit on the TOP500 list<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n4\" aria-label=\"Note 4\">4<\/a><\/sup>, training compute has doubled about every six months since the early 2010s<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n13\" id=\"nx-nrp-gs-15-c1-r13\" aria-label=\"Note 13\">13<\/a><\/sup>, and AI systems are entering hypothesis generation<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n27\" id=\"nx-nrp-gs-15-c1-r27\" aria-label=\"Note 27\">27<\/a><\/sup>. Governance is moving in parallel through UNESCO recommendations and a WHO framework on <a class=\"nx-link nx-term\" href=\"https:\/\/nexustandards.com\/standards\/nrs\/#nrs-c1\" data-tc=\"NRS-C1 dual-use-research\" data-tk=\"Nexus risk vocabulary\" data-td=\"Legitimate research whose knowledge, methods or products could also be misused to cause serious harm.\" data-ts=\"NRS-C1\" data-tr=\"draft\">dual-use research<\/a><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n25\" id=\"nx-nrp-gs-15-c1-r25\" aria-label=\"Note 25\">25<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n26\" id=\"nx-nrp-gs-15-c1-r26\" aria-label=\"Note 26\">26<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n18\" id=\"nx-nrp-gs-15-c1-r18\" aria-label=\"Note 18\">18<\/a><\/sup>.<\/p><\/div><figure class=\"nrp-fig\" id=\"nx-nrp-gs-15-c1-fig1\" aria-labelledby=\"nx-nrp-gs-15-c1-fig1-t\"><figcaption class=\"nrp-figcap\"><span class=\"nf-ui-eyebrow\">Figure 1.1<\/span><span class=\"nf-ui-title\" data-level=\"card\" id=\"nx-nrp-gs-15-c1-fig1-t\">How unevenly is research capacity spread? Researchers per million inhabitants (FTE), 2023<\/span><p class=\"nrp-fig-what\">The densest region has about fifty-seven times as many researchers per million people as the thinnest one. Spending shares follow the same order, so capacity and funding compound each other<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n2\" aria-label=\"Note 2\">2<\/a><\/sup>.<\/p><\/figcaption><div class=\"nrp-tblw\"><table class=\"nrp-tbl nrp-bars\"><thead><tr><th scope=\"col\">Item<\/th><th scope=\"col\"><span class=\"nrp-sr\">Bar, scaled to the largest value<\/span><\/th><th scope=\"col\">Value<\/th><\/tr><\/thead><tbody><tr><th scope=\"row\">Northern America<\/th><td class=\"nrp-barc\"><svg class=\"nrp-svg nrp-barsvg\" viewBox=\"0 0 100 8\" preserveAspectRatio=\"none\" aria-hidden=\"true\" focusable=\"false\"><rect class=\"nrp-track\" x=\"0\" y=\"0\" width=\"100\" height=\"8\"\/><rect class=\"nrp-bar\" x=\"0\" y=\"0\" width=\"100.0\" height=\"8\"\/><\/svg><\/td><td class=\"nrp-mono\">5006<\/td><\/tr><tr><th scope=\"row\">Europe<\/th><td class=\"nrp-barc\"><svg class=\"nrp-svg nrp-barsvg\" viewBox=\"0 0 100 8\" preserveAspectRatio=\"none\" aria-hidden=\"true\" focusable=\"false\"><rect class=\"nrp-track\" x=\"0\" y=\"0\" width=\"100\" height=\"8\"\/><rect class=\"nrp-bar\" x=\"0\" y=\"0\" width=\"80.4\" height=\"8\"\/><\/svg><\/td><td class=\"nrp-mono\">4025<\/td><\/tr><tr><th scope=\"row\">Eastern Asia<\/th><td class=\"nrp-barc\"><svg class=\"nrp-svg nrp-barsvg\" viewBox=\"0 0 100 8\" preserveAspectRatio=\"none\" aria-hidden=\"true\" focusable=\"false\"><rect class=\"nrp-track\" x=\"0\" y=\"0\" width=\"100\" height=\"8\"\/><rect class=\"nrp-bar\" x=\"0\" y=\"0\" width=\"52.6\" height=\"8\"\/><\/svg><\/td><td class=\"nrp-mono\">2632<\/td><\/tr><tr><th scope=\"row\">Latin America and the Caribbean<\/th><td class=\"nrp-barc\"><svg class=\"nrp-svg nrp-barsvg\" viewBox=\"0 0 100 8\" preserveAspectRatio=\"none\" aria-hidden=\"true\" focusable=\"false\"><rect class=\"nrp-track\" x=\"0\" y=\"0\" width=\"100\" height=\"8\"\/><rect class=\"nrp-bar\" x=\"0\" y=\"0\" width=\"13.3\" height=\"8\"\/><\/svg><\/td><td class=\"nrp-mono\">668<\/td><\/tr><tr><th scope=\"row\">Southern Asia<\/th><td class=\"nrp-barc\"><svg class=\"nrp-svg nrp-barsvg\" viewBox=\"0 0 100 8\" preserveAspectRatio=\"none\" aria-hidden=\"true\" focusable=\"false\"><rect class=\"nrp-track\" x=\"0\" y=\"0\" width=\"100\" height=\"8\"\/><rect class=\"nrp-bar\" x=\"0\" y=\"0\" width=\"6.9\" height=\"8\"\/><\/svg><\/td><td class=\"nrp-mono\">347<\/td><\/tr><tr><th scope=\"row\">Sub-Saharan Africa<\/th><td class=\"nrp-barc\"><svg class=\"nrp-svg nrp-barsvg\" viewBox=\"0 0 100 8\" preserveAspectRatio=\"none\" aria-hidden=\"true\" focusable=\"false\"><rect class=\"nrp-track\" x=\"0\" y=\"0\" width=\"100\" height=\"8\"\/><rect class=\"nrp-bar\" x=\"0\" y=\"0\" width=\"1.8\" height=\"8\"\/><\/svg><\/td><td class=\"nrp-mono\">88<\/td><\/tr><\/tbody><\/table><\/div><p class=\"nrp-fig-src\">Source: as cited in the note to this figure. Year 2023.<\/p><p class=\"nrp-fig-src\">Figure ID FIG-SECTOR-SCIENCE-GLOBAL-2026-BASELINE-01-003<\/p><\/figure><div class=\"pp-cells nrp-cells-3\"><div class=\"nrp-cell\"><span class=\"pp-metric\">88<\/span><span class=\"nrp-cell-u\">per million<\/span><p>researchers in Sub-Saharan Africa<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n2\" aria-label=\"Note 2\">2<\/a><\/sup><\/p><\/div><div class=\"nrp-cell\"><span class=\"pp-metric\">5,006<\/span><span class=\"nrp-cell-u\">per million<\/span><p>researchers in Northern America<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n2\" aria-label=\"Note 2\">2<\/a><\/sup><\/p><\/div><div class=\"nrp-cell\"><span class=\"pp-metric\">0.38<\/span><span class=\"nrp-cell-u\">%<\/span><p>of GDP spent on R&amp;D in Sub-Saharan Africa<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n2\" aria-label=\"Note 2\">2<\/a><\/sup><\/p><\/div><div class=\"nrp-cell\"><span class=\"pp-metric\">70<\/span><span class=\"nrp-cell-u\">per million<\/span><p>researchers in Least Developed Countries<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n2\" aria-label=\"Note 2\">2<\/a><\/sup><\/p><\/div><\/div><\/section><section class=\"nrp-block\" id=\"nx-nrp-gs-15-c1-s3\" aria-labelledby=\"nx-nrp-gs-15-c1-s3-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-gs-15-c1-s3-h\"><span class=\"nrp-num\">1.3<\/span><span>Twenty couplings between five systems<\/span><\/h2><p class=\"nrp-stand\">The science and engineering-centred matrix types the twenty couplings between the five core <a class=\"nx-link nx-term\" href=\"https:\/\/docs.therisk.global\/organization\/systems\" data-tc=\"Systems\" data-tk=\"Nexus Standards\" data-td=\"The twenty Nexus systems, NXS-CMD to NXS-LAB\">systems<\/a>, read for their science and engineering content. Strengths are Nexus estimates (ESTIMATED) from the cited evidence and analogue events; they set the graph that 2027 evidence will test.<\/p><figure class=\"nrp-fig\" id=\"nx-nrp-gs-15-c1-fig2\" aria-labelledby=\"nx-nrp-gs-15-c1-fig2-t\"><figcaption class=\"nrp-figcap\"><span class=\"nf-ui-eyebrow\">Figure 1.2<\/span><span class=\"nf-ui-title\" data-level=\"card\" id=\"nx-nrp-gs-15-c1-fig2-t\">Couplings between the five systems<\/span><p class=\"nrp-fig-what\">Each line is one coupling from one system to another, drawn by the strength the edition assigns. Strengths are Nexus estimates from the cited evidence and analogue events.<\/p><\/figcaption><svg class=\"nrp-svg nrp-ring\" viewBox=\"0 0 340 340\" role=\"img\" aria-label=\"Coupling ring: 20 typed couplings between water, energy, food, health and biodiversity. The matrix in the next table carries every value.\" data-nx-z=\"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\"><\/svg><ul class=\"nrp-legend\"><li><span class=\"nrp-key\" data-w=\"STRONG\"><\/span>Strong<\/li><li><span class=\"nrp-key\" data-w=\"MODERATE\"><\/span>Moderate<\/li><li><span class=\"nrp-key\" data-w=\"WEAK\"><\/span>Weak<\/li><\/ul><p class=\"nrp-fig-src\">Source: this edition&#8217;s coupling matrix (Table 1.1); status Estimated.<\/p><\/figure><div class=\"nrp-tblw\" id=\"nx-nrp-gs-15-c1-tab1\"><table class=\"nrp-tbl\"><caption><span class=\"nf-ui-eyebrow\">Table 1.1<\/span><span class=\"nrp-tbl-t\">Coupling matrix: from the row system to the column system<\/span><\/caption><thead><tr><th scope=\"col\">From, to<\/th><th scope=\"col\">WAT<\/th><th scope=\"col\">ENE<\/th><th scope=\"col\">FOO<\/th><th scope=\"col\">HLT<\/th><th scope=\"col\">BIO<\/th><\/tr><\/thead><tbody><tr><td><b>WAT<\/b> Water<\/td><td><span aria-label=\"same system\">\u00b7<\/span><\/td><td>WEAK<br><span class=\"nrp-cell-u\">hydropower research<\/span><\/td><td>MODERATE<br><span class=\"nrp-cell-u\">irrigation science and crop trials<\/span><\/td><td>WEAK<br><span class=\"nrp-cell-u\">exposure studies<\/span><\/td><td>MODERATE<br><span class=\"nrp-cell-u\">river and lake monitoring<\/span><\/td><\/tr><tr><td><b>ENE<\/b> Energy<\/td><td>WEAK<br><span class=\"nrp-cell-u\">instrument and desalination research load<\/span><\/td><td><span aria-label=\"same system\">\u00b7<\/span><\/td><td>WEAK<br><span class=\"nrp-cell-u\">processing research<\/span><\/td><td>MODERATE<br><span class=\"nrp-cell-u\">power for laboratories and clinics<\/span><\/td><td>WEAK<br><span class=\"nrp-cell-u\">field-station power<\/span><\/td><\/tr><tr><td><b>FOO<\/b> Food<\/td><td>WEAK<br><span class=\"nrp-cell-u\">farm monitoring data<\/span><\/td><td>WEAK<br><span class=\"nrp-cell-u\">bio-based fuels research<\/span><\/td><td><span aria-label=\"same system\">\u00b7<\/span><\/td><td>MODERATE<br><span class=\"nrp-cell-u\">nutrition science<\/span><\/td><td>MODERATE<br><span class=\"nrp-cell-u\">crop genetics and land-use science<\/span><\/td><\/tr><tr><td><b>HLT<\/b> Health<\/td><td>WEAK<br><span class=\"nrp-cell-u\">public health surveillance<\/span><\/td><td>WEAK<br><span class=\"nrp-cell-u\">workforce<\/span><\/td><td>MODERATE<br><span class=\"nrp-cell-u\">zoonosis and food-safety science<\/span><\/td><td><span aria-label=\"same system\">\u00b7<\/span><\/td><td>STRONG<br><span class=\"nrp-cell-u\">genomics and structural biology tools<\/span><\/td><\/tr><tr><td><b>BIO<\/b> Biodiversity<\/td><td>WEAK<br><span class=\"nrp-cell-u\">catchment monitoring<\/span><\/td><td>WEAK<br><span class=\"nrp-cell-u\">biomass research<\/span><\/td><td>MODERATE<br><span class=\"nrp-cell-u\">breeding resources<\/span><\/td><td>STRONG<br><span class=\"nrp-cell-u\">sequences, structures and medicines<\/span><\/td><td><span aria-label=\"same system\">\u00b7<\/span><\/td><\/tr><\/tbody><tfoot><tr><td colspan=\"6\">Strength: strong, moderate or weak; a Nexus estimate (status Estimated) from cited evidence and analogue events. The scale is defined in Annex A.<\/td><\/tr><\/tfoot><\/table><\/div><h3 class=\"nrp-h3\">Transmission paths<\/h3><ol class=\"nrp-rows\"><li><span class=\"nrp-rows-i\">01<\/span><p class=\"nrp-rows-t\">BIO \u2192 HLT<\/p><p class=\"nrp-rows-x\">Sequence, structure and trial data feed medicines and gene therapy.<\/p><p class=\"nrp-rows-m\"><span class=\"nrp-st\"><span class=\"nf-ui-dot\" data-tone=\"info\" aria-hidden=\"true\"><\/span>Reported<\/span> AlphaFold database and the 2023 authorisation<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n12\" id=\"nx-nrp-gs-15-c1-r12\" aria-label=\"Note 12\">12<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n17\" aria-label=\"Note 17\">17<\/a><\/sup><\/p><\/li><li><span class=\"nrp-rows-i\">02<\/span><p class=\"nrp-rows-t\">AIC \u2192 DAT \u2192 GOV<\/p><p class=\"nrp-rows-x\">Mass-produced or AI-assisted papers dilute the record and strain peer review.<\/p><p class=\"nrp-rows-m\"><span class=\"nrp-st\"><span class=\"nf-ui-dot\" data-tone=\"info\" aria-hidden=\"true\"><\/span>Reported<\/span> paper-mill case studies<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n14\" aria-label=\"Note 14\">14<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n1\" aria-label=\"Note 1\">1<\/a><\/sup><\/p><\/li><li><span class=\"nrp-rows-i\">03<\/span><p class=\"nrp-rows-t\">FIN \u2192 DAT<\/p><p class=\"nrp-rows-x\">Funding and talent concentrate capacity in a few regions.<\/p><p class=\"nrp-rows-m\"><span class=\"nrp-st\"><span class=\"nf-ui-dot\" data-tone=\"info\" aria-hidden=\"true\"><\/span>Reported<\/span> R&amp;D shares and researcher density<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n1\" aria-label=\"Note 1\">1<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n2\" aria-label=\"Note 2\">2<\/a><\/sup><\/p><\/li><li><span class=\"nrp-rows-i\">04<\/span><p class=\"nrp-rows-t\">INF \u2192 AIC<\/p><p class=\"nrp-rows-x\">Exascale and training compute decide which groups can work at the frontier.<\/p><p class=\"nrp-rows-m\"><span class=\"nrp-st\"><span class=\"nf-ui-dot\" data-tone=\"info\" aria-hidden=\"true\"><\/span>Reported<\/span> TOP500 list and compute trend<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n4\" aria-label=\"Note 4\">4<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n13\" aria-label=\"Note 13\">13<\/a><\/sup><\/p><\/li><li><span class=\"nrp-rows-i\">05<\/span><p class=\"nrp-rows-t\">TRD \u2192 DAT<\/p><p class=\"nrp-rows-x\">Co-authorship and mobility carry knowledge across borders.<\/p><p class=\"nrp-rows-m\"><span class=\"nrp-st\"><span class=\"nf-ui-dot\" data-tone=\"info\" aria-hidden=\"true\"><\/span>Reported<\/span> 22% of articles; AI researcher moves<sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n1\" aria-label=\"Note 1\">1<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-gs-15-c1-n8\" id=\"nx-nrp-gs-15-c1-r8\" aria-label=\"Note 8\">8<\/a><\/sup><\/p><\/li><\/ol><\/section><section class=\"nrp-block\" id=\"nx-nrp-gs-15-c1-s4\" aria-labelledby=\"nx-nrp-gs-15-c1-s4-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-gs-15-c1-s4-h\"><span class=\"nrp-num\">1.4<\/span><span>Reinforcing loops<\/span><\/h2><p class=\"nrp-stand\">A shock entering either system of a loop can return amplified through the other.<\/p><div class=\"nrp-tblw\" id=\"nx-nrp-gs-15-c1-tab2\"><table class=\"nrp-tbl\"><caption><span class=\"nf-ui-eyebrow\">Table 1.2<\/span><span class=\"nrp-tbl-t\">Pairs of systems where both directions are rated strong<\/span><\/caption><thead><tr><th scope=\"col\">Loop<\/th><th scope=\"col\">First direction<\/th><th scope=\"col\">Second direction<\/th><\/tr><\/thead><tbody><tr><td><span class=\"nrp-mono\">HLT and BIO<\/span><\/td><td>Health to biodiversity: genomics and structural biology tools<\/td><td>Biodiversity to health: sequences, structures and medicines<\/td><\/tr><\/tbody><tfoot><tr><td colspan=\"3\">A causal-loop reading of the matrix (Sterman, Business Dynamics, 2000): structural, from estimated strengths, not a measured feedback.<\/td><\/tr><\/tfoot><\/table><\/div><\/section><section class=\"nrp-block\" id=\"nx-nrp-gs-15-c1-notes\" aria-labelledby=\"nx-nrp-gs-15-c1-notes-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-gs-15-c1-notes-h\"><span>Notes<\/span><\/h2><p class=\"nrp-note\">Numbers are the edition&#8217;s reference numbers, so a note reads the same in every chapter. The full list, with every source and its licence, is in Annex C. <a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/gs-15\/references\/\">Annex C, references<\/a><\/p><ol class=\"nrp-notes\"><li id=\"nx-nrp-gs-15-c1-n11\"><span class=\"nrp-notes-n\">11<\/span><span>Abramson, J. et al., Accurate structure prediction of biomolecular interactions with AlphaFold 3, Nature 630, 493 to 500, 2024 (abstract and open full text read through Europe PMC). Springer Nature, London. Observation year 2024. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r11\" aria-label=\"Back to the first call of note 11\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n17\"><span class=\"nrp-notes-n\">17<\/span><span>US Food and Drug Administration (ed.), FDA Approves First Gene Therapies to Treat Patients with Sickle Cell Disease, press announcement of 8 December 2023. FDA, Silver Spring. Page read. Observation year 2023. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r17\" aria-label=\"Back to the first call of note 17\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n9\"><span class=\"nrp-notes-n\">9<\/span><span>Stanford HAI (ed.), The 2026 AI Index Report, Chapter 5 Science, chapter page with its highlights. Stanford Institute for Human-Centered AI, Stanford. Page read; the chapter PDF was not opened. Observation year 2025. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r9\" aria-label=\"Back to the first call of note 9\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n4\"><span class=\"nrp-notes-n\">4<\/span><span>TOP500 project (ed.), TOP500 list, 67th edition, June 2026 (release text read in full for the leading <a class=\"nx-link nx-term\" href=\"https:\/\/docs.therisk.global\/organization\/systems\" data-tc=\"Systems\" data-tk=\"Nexus Standards\" data-td=\"The twenty Nexus systems, NXS-CMD to NXS-LAB\">systems<\/a>). TOP500, Prometeus GmbH. Observation year 2026. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r4\" aria-label=\"Back to the first call of note 4\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n1\"><span class=\"nrp-notes-n\">1<\/span><span>NSB (ed.), Science and Engineering Indicators 2026: The State of U.S. Science and Engineering (NSB-SEP-2026-1), May 2026, National Science Board and National Center for Science and Engineering Statistics, US National Science Foundation, Alexandria. Full PDF opened; global R&amp;D, publications, collaboration, venture investment, semiconductor and doctoral-degree figures read from the text. Observation year 2024. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r1\" aria-label=\"Back to the first call of note 1\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n2\"><span class=\"nrp-notes-n\">2<\/span><span>UNESCO Institute for Statistics (ed.), UIS data API, data version 20260507 (February 2026 data release): indicators EXPGDP.TOT, RESDEN.INHAB.TFTE and FRESP.THC, world and regional aggregates. UNESCO, Montreal. Data pulled and read. Observation year 2023. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r2\" aria-label=\"Back to the first call of note 2\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n5\"><span class=\"nrp-notes-n\">5<\/span><span>POST-CLOSE, context only: arXiv (ed.), Monthly submissions statistics (monthly CSV, 1991 to November 2026; annual totals summed by the editors). Cornell University, Ithaca. Observation year 2025. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r5\" aria-label=\"Back to the first call of note 5\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n6\"><span class=\"nrp-notes-n\">6<\/span><span>Crossref (ed.), Crossref REST API, work counts by type and publication year and counts of retraction notices (update-type filter), queried live on the access date. Crossref, Oxford. Counts are subject to later registration. Observation year 2025 (series 2015 to 2025). Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r6\" aria-label=\"Back to the first call of note 6\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n14\"><span class=\"nrp-notes-n\">14<\/span><span>Richardson, R.A.K. et al., The entities enabling scientific fraud at scale are large, resilient, and growing rapidly, Proceedings of the National Academy of Sciences 122(32), 2025 (abstract and open full text record read through Europe PMC). National Academy of Sciences, Washington. Observation year 2025. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r14\" aria-label=\"Back to the first call of note 14\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n16\"><span class=\"nrp-notes-n\">16<\/span><span>Open Science Collaboration, Estimating the reproducibility of psychological science, Science 349(6251), aac4716, 2015 (abstract read through Europe PMC; full text not opened). American Association for the Advancement of Science, Washington. Observation year 2015. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r16\" aria-label=\"Back to the first call of note 16\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n13\"><span class=\"nrp-notes-n\">13<\/span><span>Sevilla, J. et al., Compute Trends Across Three Eras of Machine Learning, arXiv 2202.05924, 2022 (abstract page read). Cornell University, Ithaca. Observation year 2022. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r13\" aria-label=\"Back to the first call of note 13\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n27\"><span class=\"nrp-notes-n\">27<\/span><span>Gottweis, J. et al., Accelerating scientific discovery with Co-Scientist, arXiv 2502.18864 (version 2, 2026; abstract read through the arXiv API). Cornell University, Ithaca. Observation year 2025. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r27\" aria-label=\"Back to the first call of note 27\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n25\"><span class=\"nrp-notes-n\">25<\/span><span>UNESCO (ed.), UNESCO Recommendation on Open Science, 2021, programme page (193 Member States). UNESCO, Paris. Page read; the Recommendation text itself returned an access error. Observation year 2021. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r25\" aria-label=\"Back to the first call of note 25\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n26\"><span class=\"nrp-notes-n\">26<\/span><span>UNESCO (ed.), Recommendation on the Ethics of Artificial Intelligence, November 2021, programme page (193 Member States). UNESCO, Paris. Page read; the text itself was not opened. Observation year 2021. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r26\" aria-label=\"Back to the first call of note 26\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n18\"><span class=\"nrp-notes-n\">18<\/span><span>WHO (ed.), Global guidance framework for the responsible use of the life sciences: mitigating biorisks and governing <a class=\"nx-link nx-term\" href=\"https:\/\/nexustandards.com\/standards\/nrs\/#nrs-c1\" data-tc=\"NRS-C1 dual-use-research\" data-tk=\"Nexus risk vocabulary\" data-td=\"Legitimate research whose knowledge, methods or products could also be misused to cause serious harm.\" data-ts=\"NRS-C1\" data-tr=\"draft\">dual-use research<\/a>, 174 pages, 2022. World Health Organization, Geneva. Publication page and overview read; the full text was not opened. Observation year 2022. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r18\" aria-label=\"Back to the first call of note 18\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n12\"><span class=\"nrp-notes-n\">12<\/span><span>Varadi, M. et al., AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences, Nucleic Acids Research 52 (database issue), 368 to 375, 2024 (abstract read through Europe PMC). Oxford University Press, Oxford. Observation year 2024. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r12\" aria-label=\"Back to the first call of note 12\">back<\/a><\/span><\/li><li id=\"nx-nrp-gs-15-c1-n8\"><span class=\"nrp-notes-n\">8<\/span><span>Stanford HAI (ed.), The 2026 AI Index Report, overview page with the ten top takeaways. Stanford Institute for Human-Centered AI, Stanford. Page read; the report PDF was not opened. Observation year 2025. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-gs-15-c1-r8\" aria-label=\"Back to the first call of note 8\">back<\/a><\/span><\/li><\/ol><\/section><section class=\"nrp-block nrp-noprint\" id=\"nx-nrp-gs-15-c1-cite\" aria-labelledby=\"nx-nrp-gs-15-c1-cite-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-gs-15-c1-cite-h\"><span>Cite this chapter<\/span><\/h2><pre class=\"nrp-pre\">Valadbaygi, S. (Ed.). (2026). Chapter 1: Science is where the frontier is made. In Nexus Global Science and Engineering Frontier Risk and Resilience Report 2026: Baseline Edition, The State of the World\u2019s Science and Engineering Frontier. (Baseline Edition 2026, Report No. NR-SECTOR-SCIENCE-GLOBAL-2026-BASELINE) [Draft under review]. 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