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\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solid;border-color:inherit}#nxe-nr-gcri-editions-xt-04-agenda.nxe svg{display:none}#nxe-nr-gcri-editions-xt-04-agenda.nxe svg.nx-i{display:inline-block;width:18px;height:18px;vertical-align:-3px}#nxe-nr-gcri-editions-xt-04-agenda.nxe :where([role=\"tablist\"],[role=\"toolbar\"],[hidden],button,.nx-theme-toggle,.nx-live-slot){display:none}#nxe-nr-gcri-editions-xt-04-agenda.nxe img{max-width:100%;height:auto}<\/style><svg class=\"nx-defs\" aria-hidden=\"true\" focusable=\"false\" width=\"0\" height=\"0\"><defs><linearGradient id=\"nx-gi\" x1=\"0\" y1=\"0\" x2=\"1\" y2=\"1\"><stop offset=\"0\" class=\"nx-gi-a\"\/><stop offset=\"0.55\" class=\"nx-gi-b\"\/><stop offset=\"1\" class=\"nx-gi-c\"\/><\/linearGradient><linearGradient id=\"nx-giu\" gradientUnits=\"userSpaceOnUse\" x1=\"0\" y1=\"0\" x2=\"800\" y2=\"0\"><stop offset=\"0\" class=\"nx-gi-a\"\/><stop offset=\"0.55\" class=\"nx-gi-b\"\/><stop offset=\"1\" class=\"nx-gi-c\"\/><\/linearGradient><linearGradient id=\"nx-gp\" x1=\"0\" y1=\"0\" x2=\"1\" y2=\"1\"><stop offset=\"0\" class=\"nx-gp-a\"\/><stop offset=\"1\" class=\"nx-gp-b\"\/><\/linearGradient><\/defs><\/svg><div class=\"nrp\"><div class=\"nrp-wrap\"><p class=\"nrj-draft\" data-nrj-shared=\"draft\" role=\"note\"><strong>Draft, not yet released.<\/strong> In stewardship review. Not indexed until the first approved release.<\/p><div class=\"nrp-reader\"><nav class=\"nrp-rail\" aria-label=\"Contents of Synthetic Biology and Bioengineering 2026\"><p class=\"nf-ui-eyebrow\">Contents<\/p><ol class=\"nrp-toc\"><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Edition home<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/summary\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Executive summary<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/coupled-system\/\"><span class=\"nrp-toc-n\">1<\/span><span>Synthetic biology is a build capability and a governance test<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/findings\/\"><span class=\"nrp-toc-n\">2<\/span><span>Key findings<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/systems-and-sectors\/\"><span class=\"nrp-toc-n\">3<\/span><span>Systems and sectors at baseline<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/risk-and-capability\/\"><span class=\"nrp-toc-n\">4<\/span><span>Risks and capability<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/scenario\/\"><span class=\"nrp-toc-n\">5<\/span><span>Design capability outpaces screening and oversight<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/lenses-and-readings\/\"><span class=\"nrp-toc-n\">6<\/span><span>Readings from the other desks<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/agenda\/\" aria-current=\"page\"><span class=\"nrp-toc-n\">7<\/span><span>The 2027 agenda<\/span><\/a><ol class=\"nrp-toc-sub\"><li><a href=\"#nx-nrp-xt-04-c7-s1\">7.1 Questions for the operational series<\/a><\/li><li><a href=\"#nx-nrp-xt-04-c7-s2\">7.2 Portfolio proposed for the Q1 2027 alignment<\/a><\/li><li><a href=\"#nx-nrp-xt-04-c7-s3\">7.3 The pathway<\/a><\/li><li><a href=\"#nx-nrp-xt-04-c7-s4\">7.4 Universe 2027: evidence pack for the synthetic biology candidate mission<\/a><\/li><li><a href=\"#nx-nrp-xt-04-c7-s5\">7.5 Handoffs and routing<\/a><\/li><li><a href=\"#nx-nrp-xt-04-c7-s6\">7.6 Feeds and signal register<\/a><\/li><\/ol><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/systems-in-depth\/\"><span class=\"nrp-toc-n\">8<\/span><span>Systems in depth<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/methodology\/\"><span class=\"nrp-toc-n\">A<\/span><span>Methodology<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/data\/\"><span class=\"nrp-toc-n\">B<\/span><span>Data appendix<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/references\/\"><span class=\"nrp-toc-n\">C<\/span><span>References and record<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/full\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Complete edition, for print<\/span><\/a><\/li><\/ol><div class=\"nrp-actions\"><a class=\"nf-ui-btn\" data-variant=\"secondary\" href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/full\/\"><svg class=\"nrp-i\" viewBox=\"0 0 24 24\" aria-hidden=\"true\" focusable=\"false\"><path d=\"M6 18H4a2 2 0 0 1-2-2v-5a2 2 0 0 1 2-2h16a2 2 0 0 1 2 2v5a2 2 0 0 1-2 2h-2\"\/><path d=\"M6 9V3a1 1 0 0 1 1-1h10a1 1 0 0 1 1 1v6\"\/><rect x=\"6\" y=\"14\" width=\"12\" height=\"8\" rx=\"1\"\/><\/svg>Print or save as PDF<\/a><\/div><\/nav><article class=\"nrp-flow\" aria-labelledby=\"nx-nrp-xt-04-c7-top\"><header class=\"nrp-chap-head\" id=\"nx-nrp-xt-04-c7-top\"><ul class=\"nrp-eyerow\"><li class=\"nf-ui-eyebrow\"><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/\">Synthetic Biology and Bioengineering 2026<\/a><\/li><li class=\"nf-ui-eyebrow\">Chapter 7<\/li><\/ul><span class=\"nrp-rule\" aria-hidden=\"true\"><\/span><h1 class=\"pp-hero-title\">The 2027 agenda<\/h1><p class=\"nrp-lede\">Eight bounded questions open the 2027 synthetic biology agenda. Each comes from a baseline finding, names the initiative that will carry it and the first output due in the 2027 synthetic biology edition.<\/p><p class=\"nrp-chap-meta\"><span>5 min read<\/span><span>0 figures<\/span><span>6 tables<\/span><span>4 notes<\/span><span>NR-XTECH-SYNBIO-GLOBAL-2026-BASELINE<\/span><\/p><details class=\"nrp-toc-m\"><summary>Contents<\/summary><ol class=\"nrp-toc\"><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Edition home<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/summary\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Executive summary<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/coupled-system\/\"><span class=\"nrp-toc-n\">1<\/span><span>Synthetic biology is a build capability and a governance test<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/findings\/\"><span class=\"nrp-toc-n\">2<\/span><span>Key findings<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/systems-and-sectors\/\"><span class=\"nrp-toc-n\">3<\/span><span>Systems and sectors at baseline<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/risk-and-capability\/\"><span class=\"nrp-toc-n\">4<\/span><span>Risks and capability<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/scenario\/\"><span class=\"nrp-toc-n\">5<\/span><span>Design capability outpaces screening and oversight<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/lenses-and-readings\/\"><span class=\"nrp-toc-n\">6<\/span><span>Readings from the other desks<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/agenda\/\" aria-current=\"page\"><span class=\"nrp-toc-n\">7<\/span><span>The 2027 agenda<\/span><\/a><ol class=\"nrp-toc-sub\"><li><a href=\"#nx-nrp-xt-04-c7-s1\">7.1 Questions for the operational series<\/a><\/li><li><a href=\"#nx-nrp-xt-04-c7-s2\">7.2 Portfolio proposed for the Q1 2027 alignment<\/a><\/li><li><a href=\"#nx-nrp-xt-04-c7-s3\">7.3 The pathway<\/a><\/li><li><a href=\"#nx-nrp-xt-04-c7-s4\">7.4 Universe 2027: evidence pack for the synthetic biology candidate mission<\/a><\/li><li><a href=\"#nx-nrp-xt-04-c7-s5\">7.5 Handoffs and routing<\/a><\/li><li><a href=\"#nx-nrp-xt-04-c7-s6\">7.6 Feeds and signal register<\/a><\/li><\/ol><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/systems-in-depth\/\"><span class=\"nrp-toc-n\">8<\/span><span>Systems in depth<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/methodology\/\"><span class=\"nrp-toc-n\">A<\/span><span>Methodology<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/data\/\"><span class=\"nrp-toc-n\">B<\/span><span>Data appendix<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/references\/\"><span class=\"nrp-toc-n\">C<\/span><span>References and record<\/span><\/a><\/li><li><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/full\/\"><span class=\"nrp-toc-n\">\u00b7<\/span><span>Complete edition, for print<\/span><\/a><\/li><\/ol><\/details><\/header><section class=\"nrp-block\" id=\"nx-nrp-xt-04-c7-s1\" aria-labelledby=\"nx-nrp-xt-04-c7-s1-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-xt-04-c7-s1-h\"><span class=\"nrp-num\">7.1<\/span><span>Questions for the operational series<\/span><\/h2><ol class=\"nrp-rows\"><li><span class=\"nrp-rows-i\">Q-01<\/span><p class=\"nrp-rows-t\">How well do synthesis providers screen orders, and how do practices differ by country?<\/p><p class=\"nrp-rows-m\">INI-XT04-SCR-01 \u00b7 screening coverage; first output: screening practice register.<\/p><\/li><li><span class=\"nrp-rows-i\">Q-02<\/span><p class=\"nrp-rows-t\">What do fermentation and cell-free manufacturing need in energy, water and feedstock at commercial scale?<\/p><p class=\"nrp-rows-m\">INI-XT04-ENE-02 \u00b7 manufacturing footprint; first output: footprint estimates by process.<\/p><\/li><li><span class=\"nrp-rows-i\">Q-03<\/span><p class=\"nrp-rows-t\">Which DNA synthesis, instrument and reagent steps are single points of failure?<\/p><p class=\"nrp-rows-m\">INI-XT04-SUP-03 \u00b7 DNA supply chain; first output: dependence map.<\/p><\/li><li><span class=\"nrp-rows-i\">Q-04<\/span><p class=\"nrp-rows-t\">How much biofoundry and bioindustrial capacity exists, and where?<\/p><p class=\"nrp-rows-m\">INI-XT04-CAP-04 \u00b7 manufacturing capacity; first output: capacity table.<\/p><\/li><li><span class=\"nrp-rows-i\">Q-05<\/span><p class=\"nrp-rows-t\">How can public and private investment in synthetic biology be counted on one basis?<\/p><p class=\"nrp-rows-m\">INI-XT04-FIN-05 \u00b7 investment on a common basis; first output: investment table.<\/p><\/li><li><span class=\"nrp-rows-i\">Q-06<\/span><p class=\"nrp-rows-t\">Which national frameworks set screening or oversight rules, and how do they differ?<\/p><p class=\"nrp-rows-m\">To be admitted in 2027; first output: framework overlay.<\/p><\/li><li><span class=\"nrp-rows-i\">Q-07<\/span><p class=\"nrp-rows-t\">What workforce exists for design, biofoundry operation and biosafety oversight?<\/p><p class=\"nrp-rows-m\">To be admitted in 2027; first output: scoping note.<\/p><\/li><li><span class=\"nrp-rows-i\">Q-08<\/span><p class=\"nrp-rows-t\">Which readiness capabilities have been tested in real incidents, and which are only planned?<\/p><p class=\"nrp-rows-m\">Readiness capability register; first output: rung evidence for 15 functions.<\/p><\/li><\/ol><\/section><section class=\"nrp-block\" id=\"nx-nrp-xt-04-c7-s2\" aria-labelledby=\"nx-nrp-xt-04-c7-s2-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-xt-04-c7-s2-h\"><span class=\"nrp-num\">7.2<\/span><span>Portfolio proposed for the Q1 2027 alignment<\/span><\/h2><p class=\"nrp-stand\">Five initiatives and one <a class=\"nx-link\" href=\"https:\/\/docs.therisk.global\/organization\/programme\/universe\">Universe<\/a> mission candidate are proposed for the 2027 synthetic biology portfolio. They are programme objects: no partner, funder or member is attached to them in this edition.<\/p><div class=\"nrp-tblw\" id=\"nx-nrp-xt-04-c7-tab1\"><table class=\"nrp-tbl\"><caption><span class=\"nf-ui-eyebrow\">Table 7.1<\/span><span class=\"nrp-tbl-t\">Objects proposed for the first operational quarter<\/span><\/caption><thead><tr><th scope=\"col\">ID<\/th><th scope=\"col\">Object<\/th><th scope=\"col\">Kind<\/th><th scope=\"col\">Question<\/th><th scope=\"col\">State<\/th><\/tr><\/thead><tbody><tr><td><span class=\"nrp-mono\">INI-XT04-SCR-01<\/span><\/td><td>Screening coverage<\/td><td>Initiative<\/td><td>Q-01<\/td><td>PROPOSED<\/td><\/tr><tr><td><span class=\"nrp-mono\">INI-XT04-ENE-02<\/span><\/td><td>Manufacturing footprint<\/td><td>Initiative<\/td><td>Q-02<\/td><td>PROPOSED<\/td><\/tr><tr><td><span class=\"nrp-mono\">INI-XT04-SUP-03<\/span><\/td><td>DNA supply chain<\/td><td>Initiative<\/td><td>Q-03<\/td><td>PROPOSED<\/td><\/tr><tr><td><span class=\"nrp-mono\">INI-XT04-CAP-04<\/span><\/td><td>Manufacturing capacity<\/td><td>Initiative<\/td><td>Q-04<\/td><td>PROPOSED<\/td><\/tr><tr><td><span class=\"nrp-mono\">INI-XT04-FIN-05<\/span><\/td><td>Investment on a common basis<\/td><td>Initiative<\/td><td>Q-05<\/td><td>PROPOSED<\/td><\/tr><tr><td><span class=\"nrp-mono\">MSN-XT04-2027-01<\/span><\/td><td>Design and screening Universe mission<\/td><td>Mission<\/td><td>Q-01<\/td><td><span class=\"nrp-st\"><span class=\"nf-ui-dot\" data-tone=\"caution\" aria-hidden=\"true\"><\/span>Candidate<\/span><\/td><\/tr><\/tbody><\/table><\/div><\/section><section class=\"nrp-block\" id=\"nx-nrp-xt-04-c7-s3\" aria-labelledby=\"nx-nrp-xt-04-c7-s3-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-xt-04-c7-s3-h\"><span class=\"nrp-num\">7.3<\/span><span>The pathway<\/span><\/h2><p class=\"nrp-stand\">The synthetic biology edition reads national readiness chapters, the coupled sector reports on health, food and biosecurity, and the global edition through one governed evidence graph. At baseline the federation is designed; the global energy, health and food editions are drafted. This page states what exists today and what comes next.<\/p><ol class=\"nrp-rows\"><li><span class=\"nrp-rows-i\">01<\/span><p class=\"nrp-rows-t\">National readiness chapters<\/p><p class=\"nrp-rows-x\">biotechnology and biosecurity readiness in each national edition<\/p><p class=\"nrp-rows-m\">IN PREPARATION \u00b7 national baselines<\/p><\/li><li><span class=\"nrp-rows-i\">02<\/span><p class=\"nrp-rows-t\">Sector couplings<\/p><p class=\"nrp-rows-x\">GS-03 food \u00b7 GS-04 health \u00b7 XT-05 genomics \u00b7 SR-08 biosecurity<\/p><p class=\"nrp-rows-m\">GS-04 DRAFTED \u00b7 sector baselines<\/p><\/li><li><span class=\"nrp-rows-i\">03<\/span><p class=\"nrp-rows-t\">Technology system model<\/p><p class=\"nrp-rows-x\">platforms, DNA supply, manufacturing, workforce, governance<\/p><p class=\"nrp-rows-m\">v0 SPECIFIED \u00b7 v1 with federation evidence<\/p><\/li><li><span class=\"nrp-rows-i\">04<\/span><p class=\"nrp-rows-t\">Strategic links<\/p><p class=\"nrp-rows-x\">SR-08 health security \u00b7 SR-13 strategic technology<\/p><p class=\"nrp-rows-m\">PLANNED \u00b7 strategic baselines<\/p><\/li><li><span class=\"nrp-rows-i\">05<\/span><p class=\"nrp-rows-t\">Universe<\/p><p class=\"nrp-rows-x\">annual proving environment<\/p><p class=\"nrp-rows-m\">CANDIDATE MISSION \u00b7 mandate in 2027<\/p><\/li><li><span class=\"nrp-rows-i\">06<\/span><p class=\"nrp-rows-t\">XT-04 report<\/p><p class=\"nrp-rows-x\">this series<\/p><p class=\"nrp-rows-m\">BASELINE DRAFT \u00b7 2027 annual edition<\/p><\/li><li><span class=\"nrp-rows-i\">07<\/span><p class=\"nrp-rows-t\">Evidence and correction<\/p><p class=\"nrp-rows-x\">one graph, many projections<\/p><p class=\"nrp-rows-m\">OPEN \u00b7 first correction cycle in 2027<\/p><\/li><\/ol><\/section><section class=\"nrp-block\" id=\"nx-nrp-xt-04-c7-s4\" aria-labelledby=\"nx-nrp-xt-04-c7-s4-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-xt-04-c7-s4-h\"><span class=\"nrp-num\">7.4<\/span><span>Universe 2027: evidence pack for the synthetic biology candidate mission<\/span><\/h2><ol class=\"nrp-rows\"><li><span class=\"nrp-rows-i\">01<\/span><p class=\"nrp-rows-x\">Mandate<\/p><\/li><li><span class=\"nrp-rows-i\">02<\/span><p class=\"nrp-rows-x\">Core Build \u00b7 1 month<\/p><\/li><li><span class=\"nrp-rows-i\">03<\/span><p class=\"nrp-rows-x\">Action \u00b7 1 week<\/p><\/li><li><span class=\"nrp-rows-i\">04<\/span><p class=\"nrp-rows-x\">Evidence seal<\/p><\/li><li><span class=\"nrp-rows-i\">05<\/span><p class=\"nrp-rows-x\">Portfolio correction<\/p><\/li><li><span class=\"nrp-rows-i\">06<\/span><p class=\"nrp-rows-x\">Next mandate<\/p><\/li><\/ol><div class=\"nrp-tblw\" id=\"nx-nrp-xt-04-c7-tab2\"><table class=\"nrp-tbl\"><caption><span class=\"nf-ui-eyebrow\">Table 7.2<\/span><span class=\"nrp-tbl-t\">Universe 2027: evidence pack for the synthetic biology candidate mission<\/span><\/caption><thead><tr><th scope=\"col\">Item<\/th><th scope=\"col\">Record<\/th><th scope=\"col\">State<\/th><th scope=\"col\">Timing<\/th><\/tr><\/thead><tbody><tr><td>F1<\/td><td>Annual mandate record<\/td><td>PLANNED<\/td><td>after the Q2 2027 alignment<\/td><\/tr><tr><td>F2<\/td><td>Core Build record<\/td><td>PLANNED<\/td><td>one month before the exercise<\/td><\/tr><tr><td>F3<\/td><td>Exercise evidence<\/td><td>PLANNED<\/td><td>during the Action week<\/td><\/tr><tr><td>F4<\/td><td>Decision packets<\/td><td>PLANNED<\/td><td>exercise state only<\/td><\/tr><tr><td>F5<\/td><td>Proof receipts<\/td><td>PLANNED<\/td><td>scoped to each recorded check<\/td><\/tr><tr><td>F6<\/td><td>After-action report<\/td><td>PLANNED<\/td><td>within one quarter<\/td><\/tr><tr><td>F7<\/td><td>Upgrade docket<\/td><td>PLANNED<\/td><td>routed to the Portfolio<\/td><\/tr><tr><td>F8<\/td><td>Portfolio renewal<\/td><td>PLANNED<\/td><td>2027 global annual edition<\/td><\/tr><tr><td>F9<\/td><td>Public synthesis<\/td><td>PLANNED<\/td><td>public-safe extracts only<\/td><\/tr><\/tbody><\/table><\/div><h3 class=\"nrp-h3\">Mission<\/h3><dl class=\"nrp-dl\"><dt>ID<\/dt><dd>MSN-XT04-2027-01 \u00b7 Design and screening Universe mission<\/dd><dt>Role spine<\/dt><dd>Leadership sponsor \u00b7 Institutional anchor \u00b7 Mission lead: drawn from national pathways<\/dd><dt>Receiving actors<\/dt><dd>to be identified with the mandate<\/dd><\/dl><aside class=\"nrp-call\"><p class=\"nf-ui-eyebrow\">boundary<\/p><p>Simulation success is not deployment approval; demonstration is not certification; finance readiness is not financing secured.<\/p><\/aside><\/section><section class=\"nrp-block\" id=\"nx-nrp-xt-04-c7-s5\" aria-labelledby=\"nx-nrp-xt-04-c7-s5-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-xt-04-c7-s5-h\"><span class=\"nrp-num\">7.5<\/span><span>Handoffs and routing<\/span><\/h2><p class=\"nrp-stand\">Where the baseline\u2019s findings go next. A handoff routes a finding for awareness, review or work; it transfers no authority.<\/p><div class=\"nrp-tblw\" id=\"nx-nrp-xt-04-c7-tab3\"><table class=\"nrp-tbl\"><caption><span class=\"nf-ui-eyebrow\">Table 7.3<\/span><span class=\"nrp-tbl-t\">Handoffs and routing<\/span><\/caption><thead><tr><th scope=\"col\">Finding<\/th><th scope=\"col\">Routed to<\/th><th scope=\"col\">Purpose<\/th><th scope=\"col\">Class<\/th><\/tr><\/thead><tbody><tr><td>BLD-001 \u00b7 recoded genomes<\/td><td>INI-XT04-CAP-04<\/td><td>manufacturing capacity<\/td><td>PUBLIC<\/td><\/tr><tr><td>CLN-004 \u00b7 engineered therapies<\/td><td>INI-XT04-FIN-05<\/td><td>investment on a common basis<\/td><td>PUBLIC<\/td><\/tr><tr><td>SEC-005 \u00b7 screening gaps<\/td><td>INI-XT04-SCR-01<\/td><td>screening coverage<\/td><td>PUBLIC<\/td><\/tr><tr><td>GOV-007 \u00b7 US framework<\/td><td>regional consortia<\/td><td>framework overlay<\/td><td>PUBLIC<\/td><\/tr><tr><td>GOV-009 \u00b7 EU proposal<\/td><td>regional consortia<\/td><td>framework overlay<\/td><td>PUBLIC<\/td><\/tr><tr><td>GOV-010 \u00b7 OECD and CBD<\/td><td>INI-XT04-SUP-03<\/td><td>DNA supply chain<\/td><td>PUBLIC<\/td><\/tr><tr><td>FIN-011 \u00b7 company filings<\/td><td>INI-XT04-ENE-02 \u00b7 key F review<\/td><td>manufacturing footprint<\/td><td>PUBLIC<\/td><\/tr><tr><td>SYS-012 \u00b7 compound pathway<\/td><td>MSN-XT04-2027-01<\/td><td>Universe candidate<\/td><td>CONSORTIUM<\/td><\/tr><\/tbody><\/table><\/div><div class=\"nrp-tblw\" id=\"nx-nrp-xt-04-c7-tab4\"><table class=\"nrp-tbl\"><caption><span class=\"nf-ui-eyebrow\">Table 7.4<\/span><span class=\"nrp-tbl-t\">Routing rules by publication class<\/span><\/caption><thead><tr><th scope=\"col\">Class<\/th><th scope=\"col\">Where it goes<\/th><th scope=\"col\">Who can see it<\/th><\/tr><\/thead><tbody><tr><td>PUBLIC<\/td><td>the published edition and its evidence bundle<\/td><td>anyone<\/td><\/tr><tr><td>CONSORTIUM<\/td><td>governed rooms of the federation<\/td><td>consortium members under agreement<\/td><\/tr><tr><td>CONTROLLED<\/td><td>need-to-know channels<\/td><td>named competent actors only<\/td><\/tr><\/tbody><\/table><\/div><aside class=\"nrp-call\"><p class=\"nf-ui-eyebrow\">CODES ARE NOT JOINS<\/p><p>Series codes in this edition (XT-04 and its relatives) are <a class=\"nx-link\" href=\"https:\/\/docs.therisk.global\/organization\/programme\/reports\">Reports<\/a> codes. Codes in other indices can look alike. This edition makes no join on a code alone: a join needs a registry record that names both subjects.<\/p><\/aside><aside class=\"nrp-call\"><p class=\"nf-ui-eyebrow\">boundary<\/p><p>Handoffs carry findings to Nexus programme objects and steward reviews. States and organisations receive public editions as published; nothing here instructs them.<\/p><\/aside><\/section><section class=\"nrp-block\" id=\"nx-nrp-xt-04-c7-s6\" aria-labelledby=\"nx-nrp-xt-04-c7-s6-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-xt-04-c7-s6-h\"><span class=\"nrp-num\">7.6<\/span><span>Feeds and signal register<\/span><\/h2><div class=\"nrp-tblw\" id=\"nx-nrp-xt-04-c7-tab5\"><table class=\"nrp-tbl\"><caption><span class=\"nf-ui-eyebrow\">Table 7.5<\/span><span class=\"nrp-tbl-t\">Feeds watched from 2027<\/span><\/caption><thead><tr><th scope=\"col\">Feed<\/th><th scope=\"col\">Producer<\/th><th scope=\"col\">Latency<\/th><th scope=\"col\">Feeds into<\/th><\/tr><\/thead><tbody><tr><td>Journals and preprint servers on genome writing and design<\/td><td>peer review and preprints<\/td><td>continuous<\/td><td>BLD-001<\/td><\/tr><tr><td>Regulator announcements on engineered therapies<\/td><td>US Food and Drug Administration<\/td><td>per event<\/td><td>CLN-004<\/td><\/tr><tr><td>Screening and dual-use policy pages<\/td><td>agencies and industry consortia<\/td><td>per release<\/td><td>SEC-005<\/td><\/tr><tr><td>EU Biotech Act pages<\/td><td>European Commission<\/td><td>per release<\/td><td>GOV-009<\/td><\/tr><tr><td>OECD science and technology policy papers<\/td><td>OECD<\/td><td>per release<\/td><td>GOV-010<\/td><\/tr><tr><td>Company earnings releases<\/td><td>Twist Bioscience, Ginkgo Bioworks<\/td><td>quarterly<\/td><td>FIN-011<\/td><\/tr><tr><td>CBD synthetic biology page<\/td><td>CBD secretariat<\/td><td>per meeting<\/td><td>GOV-010<\/td><\/tr><\/tbody><\/table><\/div><h3 class=\"nrp-h3\">Escalation routes<\/h3><ul class=\"nrp-chips\"><li class=\"nf-ui-chip\">none \u00b7 keep monitoring<\/li><li class=\"nf-ui-chip\">research question<\/li><li class=\"nf-ui-chip\">project<\/li><li class=\"nf-ui-chip\">risk object<\/li><li class=\"nf-ui-chip\">annual publication<\/li><li class=\"nf-ui-chip\">signal report<\/li><\/ul><div class=\"nrp-tblw\" id=\"nx-nrp-xt-04-c7-tab6\"><table class=\"nrp-tbl\"><caption><span class=\"nf-ui-eyebrow\">Table 7.6<\/span><span class=\"nrp-tbl-t\">Signals at baseline<\/span><\/caption><thead><tr><th scope=\"col\">ID<\/th><th scope=\"col\">Signal<\/th><th scope=\"col\">Corroboration<\/th><th scope=\"col\">Systems<\/th><th scope=\"col\">Route<\/th><\/tr><\/thead><tbody><tr><td>SIG-XT04-001<\/td><td>A 57-codon genetic code was reported in 2025<sup class=\"nrp-fn\"><a href=\"#nx-nrp-xt-04-c7-n1\" id=\"nx-nrp-xt-04-c7-r1\" aria-label=\"Note 1\">1<\/a><\/sup><\/td><td>CORROBORATED<\/td><td>BLD<\/td><td>research question Q-05<\/td><\/tr><tr><td>SIG-XT04-002<\/td><td>Screening tools missed redesigned sequences in a 2025 study<sup class=\"nrp-fn\"><a href=\"#nx-nrp-xt-04-c7-n13\" id=\"nx-nrp-xt-04-c7-r13\" aria-label=\"Note 13\">13<\/a><\/sup><\/td><td>PARTIAL<\/td><td>SEC \u00b7 DAT<\/td><td>research question Q-01<\/td><\/tr><tr><td>SIG-XT04-003<\/td><td>No public replacement for the US framework was found<sup class=\"nrp-fn\"><a href=\"#nx-nrp-xt-04-c7-n26\" id=\"nx-nrp-xt-04-c7-r26\" aria-label=\"Note 26\">26<\/a><\/sup><sup class=\"nrp-fn\"><a href=\"#nx-nrp-xt-04-c7-n27\" id=\"nx-nrp-xt-04-c7-r27\" aria-label=\"Note 27\">27<\/a><\/sup><\/td><td>PARTIAL<\/td><td>GOV<\/td><td>research question Q-06<\/td><\/tr><\/tbody><\/table><\/div><aside class=\"nrp-call\"><p class=\"nf-ui-eyebrow\">boundary<\/p><p>A signal is not a warning. Signal records never substitute for official alerting or early-warning authorities, and they bypass no publication control.<\/p><\/aside><\/section><section class=\"nrp-block\" id=\"nx-nrp-xt-04-c7-notes\" aria-labelledby=\"nx-nrp-xt-04-c7-notes-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-xt-04-c7-notes-h\"><span>Notes<\/span><\/h2><p class=\"nrp-note\">Numbers are the edition&#8217;s reference numbers, so a note reads the same in every chapter. The full list, with every source and its licence, is in Annex C. <a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/references\/\">Annex C, references<\/a><\/p><ol class=\"nrp-notes\"><li id=\"nx-nrp-xt-04-c7-n1\"><span class=\"nrp-notes-n\">1<\/span><span>Robertson, W.E. et al., Escherichia coli with a 57-codon genetic code, Science 390 (6771), eady4368, published 23 October 2025 (record read via PubMed, PMID 40743368; the record gives a 4 megabase synthetic genome and six replaced sense codons). American Association for the Advancement of Science, Washington. Observation year 2025. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-xt-04-c7-r1\" aria-label=\"Back to the first call of note 1\">back<\/a><\/span><\/li><li id=\"nx-nrp-xt-04-c7-n13\"><span class=\"nrp-notes-n\">13<\/span><span>Strengthening nucleic acid biosecurity screening against generative protein design tools, Science 390 (6768), 82 to 87, 2025 (record read via Europe PMC; abstract only; no method detail used). American Association for the Advancement of Science, Washington. Observation year 2025. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-xt-04-c7-r13\" aria-label=\"Back to the first call of note 13\">back<\/a><\/span><\/li><li id=\"nx-nrp-xt-04-c7-n26\"><span class=\"nrp-notes-n\">26<\/span><span>UNVERIFIED, not opened: Executive Order 14292, Improving the Safety and Security of Biological Research, 5 May 2025 (90 days to revise or replace the framework), taken from search-result summaries; a fetch of an explainer page was refused by the fetch tool. The White House, Washington. Observation year 2025. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-xt-04-c7-r26\" aria-label=\"Back to the first call of note 26\">back<\/a><\/span><\/li><li id=\"nx-nrp-xt-04-c7-n27\"><span class=\"nrp-notes-n\">27<\/span><span>UNVERIFIED, not opened: Congressional Research Service (ed.), report on artificial intelligence and biosecurity risks (reported in July 2026 as unable to determine whether the 2024 framework or the 2025 policy had been revised), taken from a trade news summary. Library of Congress, Washington. Observation year 2026. Accessed 2026-11-03.<a class=\"nrp-notes-back\" href=\"#nx-nrp-xt-04-c7-r27\" aria-label=\"Back to the first call of note 27\">back<\/a><\/span><\/li><\/ol><\/section><section class=\"nrp-block nrp-noprint\" id=\"nx-nrp-xt-04-c7-cite\" aria-labelledby=\"nx-nrp-xt-04-c7-cite-h\"><h2 class=\"nrp-h2\" id=\"nx-nrp-xt-04-c7-cite-h\"><span>Cite this chapter<\/span><\/h2><pre class=\"nrp-pre\">Valadbaygi, S. (Ed.). (2026). Chapter 7: The 2027 agenda. In Exponential Technology Report 2026: Synthetic Biology and Bioengineering (Baseline Edition 2026, Report No. NR-XTECH-SYNBIO-GLOBAL-2026-BASELINE) [Draft under review]. The Global Centre for Risk and Innovation (GCRI).<\/pre><p class=\"nrp-note\">Every citation form of the whole report, BibTeX and RIS included, is on the edition home. <a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/#nx-nrp-xt-04-land-cite\">Cite this report<\/a><\/p><\/section><nav class=\"nrp-pager\" aria-label=\"Previous and next\"><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/lenses-and-readings\/\" rel=\"prev\"><span class=\"nf-ui-eyebrow\">Previous \u00b7 Chapter 6<\/span><span class=\"nrp-pager-t\">Readings from the other desks<\/span><\/a><a href=\"https:\/\/therisk.global\/nexus-reports\/editions\/xt-04\/systems-in-depth\/\" rel=\"next\"><span class=\"nf-ui-eyebrow\">Next \u00b7 Chapter 8<\/span><span class=\"nrp-pager-t\">Systems in depth<\/span><\/a><\/nav><\/article><\/div><\/div><\/div><div class=\"nrp-noprint\"><section id=\"nx-sec-nr-gateway\" class=\"nx-section\" data-hue=\"systemic\" data-tone=\"alt\" aria-labelledby=\"nx-nr-gateway-h\"><div class=\"nx-container\"><div class=\"nx-section-head\"><div class=\"nx-eyebrow-row\"><span class=\"nx-eyebrow\">Reports<\/span><span class=\"nx-rule\" aria-hidden=\"true\"><\/span><span class=\"nx-eyebrow\">Contribute<\/span><\/div><h2 id=\"nx-nr-gateway-h\" class=\"nx-section-title\">Send evidence or a correction on Synthetic Biology and Bioengineering.<\/h2><p class=\"nx-lede\">Reports is the Consortium&#8217;s quarterly publication, written by six desks. This page sits with the Global Centre for Risk and Innovation (GCRI) <a class=\"nx-link nx-term\" href=\"https:\/\/docs.therisk.global\/organization\/systems\" data-tc=\"Systems\" data-tk=\"Nexus Standards\" data-td=\"The twenty Nexus systems, NXS-CMD to NXS-LAB\">Systems<\/a> Evidence desk. What you know about this subject can become evidence, a case or a correction in the next edition, credited to you and published under CC BY 4.0 where it is your own work. Sent to the wrong desk, it is forwarded, not refused.<\/p><div class=\"nx-chips\"><span class=\"nx-chip\">GCRI Systems Evidence desk<\/span><span class=\"nx-chip\">Exponential Technology<\/span><\/div><\/div><div class=\"nx-section-body\"><ul class=\"nx-dest\"><li><a class=\"nx-dest-card\" href=\"https:\/\/therisk.global\/nexus-reports\/write-to-us\/contact\/\"><span class=\"nx-dest-top\"><span class=\"nx-dest-rel\">Email<\/span><span class=\"nx-dest-host\">Gateway GW-GCRI<\/span><\/span><span class=\"nx-dest-title\">Send it from this page<\/span><span class=\"nx-dest-why\">Evidence, a correction, a case, a method, a review, a translation or profile input. It arrives tagged with this page, so the editor who owns it receives it.<\/span><span class=\"nx-dest-go\" aria-hidden=\"true\"><svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/span><\/a><\/li><li><a class=\"nx-dest-card\" href=\"https:\/\/therisk.global\/nexus-reports\/open-science\/#nx-sec-zenodo\"><span class=\"nx-dest-top\"><span class=\"nx-dest-rel\">Zenodo<\/span><span class=\"nx-dest-host\">Open deposit<\/span><\/span><span class=\"nx-dest-title\">Deposit it and submit to the community<\/span><span class=\"nx-dest-why\">Publish your own record on Zenodo with your ORCID iD, then submit it to the Reports community there. Curators review it; the DOI stays yours.<\/span><span class=\"nx-dest-go\" aria-hidden=\"true\"><svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/span><\/a><\/li><li><a class=\"nx-dest-card\" href=\"https:\/\/therisk.global\/nexus-reports\/contribute\/#nx-sec-routing\"><span class=\"nx-dest-top\"><span class=\"nx-dest-rel\">Reports<\/span><span class=\"nx-dest-host\">GCRI<\/span><\/span><span class=\"nx-dest-title\">See which desk takes what you have<\/span><span class=\"nx-dest-why\">The routing table opens the contribution page: what you have, the desk that takes it, how each contribution is reviewed and credited, and the licence.<\/span><span class=\"nx-dest-go\" aria-hidden=\"true\"><svg class=\"nx-arrow\" viewBox=\"0 0 16 16\" aria-hidden=\"true\"><path d=\"M3 8h10M9 4l4 4-4 4\"\/><\/svg><\/span><\/a><\/li><\/ul><div class=\"nx-live-slot\" data-nxf-slot=\"contribute\" data-nxf-kind=\"workflow\" data-nxf-resource=\"nexus:\/\/gcri\/nexus-reports\/editions\/xt-04\/agenda#contribute\" data-nxf-title=\"Contribute evidence\" data-nxf-height=\"480\" hidden><\/div><p class=\"nx-note nx-mt-3\">Never send personal data, sensitive infrastructure detail or anything you have no right to share. A contribution is reviewed before use; sending it confers no authorship or editorial rights, and sponsorship never buys a finding.<\/p><\/div><\/div><\/section><\/div><p class=\"nx-note\" data-nr-rights=\"true\"><a class=\"nx-link\" rel=\"license\" href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\/\">CC BY 4.0<\/a> Free to read. Text and figures: CC BY 4.0. Data: CC0 1.0. Authors keep copyright. Published by GCRI Canada.<\/p><section class=\"nx-section nx-deeper-band\" aria-labelledby=\"nx-deeper-erisk-global-nexus-reports-editions-xt-04-agenda-h\"><div class=\"nx-container\"><nav class=\"nx-deeper\" aria-labelledby=\"nx-deeper-erisk-global-nexus-reports-editions-xt-04-agenda-h\" data-nx-deeper=\"3\" data-nx-resources=\"1 1 1\"><h2 class=\"nx-deeper-h\" id=\"nx-deeper-erisk-global-nexus-reports-editions-xt-04-agenda-h\">Go deeper<\/h2><ul><li><a href=\"https:\/\/docs.therisk.global\/organization\/model\/scenarios\/urban-flood\" data-ext><span class=\"nx-deeper-k\">Documentation:<\/span> Urban flood<span class=\"nx-deeper-x\" aria-hidden=\"true\">\u2197<\/span><span class=\"nx-deeper-sr\"> (opens another site)<\/span><\/a><\/li><li><a href=\"https:\/\/risksacademy.com\/risk-science\/risk-information-standards\/\" data-ext><span class=\"nx-deeper-k\">Academy:<\/span> Risk information standards and interoperability<span class=\"nx-deeper-x\" aria-hidden=\"true\">\u2197<\/span><span class=\"nx-deeper-sr\"> (opens another site)<\/span><\/a><\/li><li><a href=\"https:\/\/nexustandards.com\/data\/identification-standards\/\" data-ext><span class=\"nx-deeper-k\">Standards:<\/span> Identification (the UNI)<span class=\"nx-deeper-x\" aria-hidden=\"true\">\u2197<\/span><span class=\"nx-deeper-sr\"> (opens another site)<\/span><\/a><\/li><\/ul><\/nav><\/div><\/section><\/div><\/div><script class=\"_iub_cs_skip\">window.__nxMount ? window.__nxMount(document.currentScript) : null;<\/script><style>@media print { @page { margin: 20mm 17mm 20mm 17mm; @top-left { content: \"Nexus Reports\"; font: 500 7.5pt \"IBM Plex Mono\", monospace; color: #4a4a4a; } @top-right { content: \"Synthetic Biology and Bioengineering 2026 \\0000b7  Chapter 7\"; font: 400 7.5pt \"IBM Plex Sans\", sans-serif; color: #4a4a4a; } @bottom-left { content: \"NR-XTECH-SYNBIO-GLOBAL-2026-BASELINE \\0000b7  Draft, not released\"; font: 400 7pt \"IBM Plex Mono\", monospace; color: #4a4a4a; } @bottom-center { content: \"CC BY 4.0. 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