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GCRI · Bioteknologi dan Biosekuriti

Ilmu molekuler dan hayati untuk bioteknologi dan biosekuriti

How molecular and life sciences is applied in Biotechnology and Biosecurity. Molecular and life sciences study the structure and function of living sistem from genes and proteins to cells and organisms. They underpin the understanding of pathogens, resistance, toxicity and biological innovation.

01Daftar

Molecular and life sciences for biotechnology and biosecurity on the record.

Catatan metodeMetode STEM
  1. MetodeIlmu molekuler dan ilmu hayati
  2. PengelolaBioteknologi dan Biosekuriti
  3. Diterapkan diBioteknologi dan Biosekuriti
  4. PemeriksaanValidasi
  5. Halaman kanonisSTEM Commons
02Permohonan

What molecular and life sciences does here.

Molecular and life sciences study the structure and function of living sistem from genes and proteins to cells and organisms. They underpin the understanding of pathogens, resistance, toxicity and biological innovation. In health and biosecurity and food and agriculture, life sciences support pathogen characterisation, resistansi antimikroba tracking and biosecurity assessment. They inform how biological threats might spread through health, agriculture and trade. The canonical description is on STEM Commons.

  1. 01

    Methods used here

    genome sequencing and assembly; phylogenetic analysis; functional assays; proteomics and metabolomics; cell and tissue culture; bioinformatic pipelines.

  2. 02

    Validasi

    Results are confirmed through biological replicates, independent laboratories and orthogonal assays. Reference standards and proficiency testing check analytical accuracy.

03Simulator

SEIR pada jaringan tempat.

An outbreak seeded in one place spreads through a small-world network by the share of contacts people make elsewhere; play it to see the order of arrival and how the timing of measures moves the peak. Teaching model with stated illustrative values, not a prediction.

Kendali

Bilangan reproduksi dasar R0
2.5
Masa laten
3,0 hari
Masa menular
5,0 hari
Pangsa kontak yang terjadi di tempat lain
8%
Tempat dalam jaringan
24
Langkah dimulai pada hari
40
Pengurangan kontak dari langkah-langkah
40%
Hari yang disimulasikan
240 hari

Pembacaan

Puncak infeksi baru
4.42 per 1,000 a day
Hari puncak
176
Pangsa yang pernah terinfeksi
56%
Tempat yang dijangkau
100%
Bilangan reproduksi di bawah langkah-langkah
1.50
Angka, metode, dan sumber
HariInfeksi baru per 1 000Kumulatif terinfeksi (%)
00.000.0
170.030.0
340.310.2
510.921.4
681.563.5
852.116.7
1022.3910.5
1192.6114.8
1363.1219.6
1533.8725.6
1704.3832.7
1874.3040.2
2043.6547.0
2212.5652.2
2381.4555.6

Metode

  1. Kompartemen SEIR Kermack and McKendrick (1927), Proc. R. Soc. A 115
  2. Keterkaitan metapopulasi menurut mobilitas Balcan and others (2009), PNAS 106
  3. Jaringan dunia kecil Watts and Strogatz (1998), Nature 393
  4. Pemodelan penyakit menular Keeling and Rohani (2008), Princeton University Press
  5. Kipas ketidakpastian (Monte Carlo parameter) Spiegelhalter, Pearson and Short (2011), Visualising uncertainty about the future, Science 333
  6. Sensitivitas satu per satu (tornado) Saltelli and others (2008), Global Sensitivity Analysis: The Primer, Wiley

Data

The model runs on the teaching values set by the controls. To calibrate it for a place, read it against these admitted layers and series, which this page’s map can draw:

  • Kota Natural Earth
  • Bandar udara Natural Earth
  • Jalan utama Natural Earth
SEIR pada jaringan tempat. Model pengajaran ilustratif: model ini berjalan pada nilai yang ditetapkan oleh kontrol, bukan pada data terukur. Metode: Kompartemen SEIR (Kermack dan McKendrick (1927), Proc. R. Soc. A 115); Penggandengan metapopulasi melalui mobilitas (Balcan dan lainnya (2009), PNAS 106); Jaringan dunia kecil (Watts dan Strogatz (1998), Nature 393).
04Data

Apa yang digunakan metode ini.

Datasets and records used by molecular and life sciences on this platform, with the role each plays and the label its values carry. Sources are listed in register sumber.

DataPeranLabel
Sequencing instrumentsMasukanTERAMATI
Public sequence repositoriesMasukanTERAMATI
BiobanksMasukanTERAMATI
Laboratory assaysMasukanTERAMATI
Structural biology instrumentsMasukanTERAMATI
05Metode dan bukti

The model, the data and the uncertainty.

Model, asumsi, data, dan ketidakpastiannya, dalam bentuk yang akan diperiksa ilmuwan atau insinyur. Strukturnya mengikuti metode yang dipublikasikan. Nilai yang digambar bersifat ilustratif, bukan temuan.

Pita ketidakpastian

How far the outlook for molecular and life sciences for biotechnology and biosecurity could spread, shown as ranges rather than a single line.

Sekarang+5+10+15+20+25+30 thntinggirendahrentang sangat mungkinrentang mungkin
Estimasi tengah
median ansambel
Rentang
mungkin dan sangat mungkin, dalam bahasa terkalibrasi IPCC
Ansambel
anggota, skenario, dan kondisi awal dinyatakan
Baca bersama
sensitivitas hasil terhadap setiap masukan
Sebaran ensambel ilustratif pada skala indeks; bentuknya mengikuti panduan ketidakpastian IPCC. Bukan proyeksi.
Prinsip panduan FAIR · GO FAIR dan FORCE11W3C PROV · World Wide Web ConsortiumPanduan penanganan ketidakpastian secara konsisten · IPCCCEOS Analysis Ready Data · Committee on Earth Observation Satellites
06Validasi

Cara hasil diperiksa.

Results are confirmed through biological replicates, independent laboratories and orthogonal assays. Reference standards and proficiency testing check analytical accuracy.

Laboratory findings do not always translate to organisms or populations. Sampling bias in sequence databases limits generalisation.

08Pengelolaan

Siapa yang memelihara metode ini.

Biotechnology and Biosecurity stewards molecular and life sciences for the Consortium and reviews how it is applied across platforms.

09Pertanyaan

Tanya jawab.

What are the limits of molecular and life sciences in this field?
Laboratory findings do not always translate to organisms or populations. Sampling bias in sequence databases limits generalisation.
Bagaimana hasil diperiksa?
Results are confirmed through biological replicates, independent laboratories and orthogonal assays. Reference standards and proficiency testing check analytical accuracy.
Apakah nilai di halaman ini nyata?
The data names, roles and checks are real descriptions of practice. The canvas shows a design of the method’s use, not a run; no result is reported here.
Di mana lagi metode ini diterapkan?
Observatory Halaman metode kanonis mencantumkan setiap platform yang menerapkannya.
LaporanBerkontribusi

Kontribusikan bukti dari halaman ini.

Laporan is the Consortium’s quarterly publication. What you know about this subject can become evidence, a case or a correction in the next edition, credited to you and published under CC BY 4.0 where it is your own work.

GCRIBioteknologi dan BiosekuritiTeknologi EksponensialRingkasan Bukti
Bioteknologi dan Biosekuriti

Bawa metode, dataset, atau pertanyaan.

Informasi dan pertanyaan sudah terbuka hari ini. Sebuah pertanyaan menerima nomor referensi dan menyebutkan langkah berikutnya; lamaran, pembayaran, alokasi komputasi, dan pendaftaran hanya dibuka ketika tim, ketentuan, dan kapasitas tinjauannya tersedia.