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GCRI · Labs

再現性とネガティブな結果

Science corrects itself only when failures are recorded: replications that did not reproduce, experiments that found nothing, errors found after publication. Many of these records never appear, so the published literature overstates effects and certainty. This page sets out how irreproducibility arises, how replication and correction work, which records exist, and what editors, integrity offices and funders rely on when they correct or retract.

02質問

Reproducibility and negative results: how the risk develops.

Failure records and corrections. The dossier below sets out how the risk develops, what is measured, where the data come from, how it is modelled and who decides.

メカニズム

Publication bias filters the record

Significant, novel results are more likely to be written up, accepted and cited than null ones. The literature then shows a biased sample of what was studied, and meta-analyses inherit the bias.

メカニズム

Errors propagate through citation

A flawed or retracted paper keeps being cited, often without mention of its status. Reviews, guidelines and later studies that build on it carry the error forward, sometimes long after the notice.

メカニズム

Reproduction fails for ordinary reasons

Missing code, undocumented software versions, unshared reagents, unclear methods and lost raw data stop others from repeating an analysis or experiment, even when the original work was honest.

メカニズム

Correction is slow and uneven

Investigations take time, journals differ in how they flag problems, and retraction notices can be vague. Readers may not learn that a paper was corrected, and databases may not carry the notice forward.

03監視

プロトコルと追試のボード。

このテーマを追跡するためにチームが使う画面:その指標、状態、決定。名前は例であり、値はイメージです。

プロトコルと追試のボード

Reproducibility and negative results · Labs · Quarter 1

実行中の 2 つの反復試験GCRI・Labs

プロトコル

PR-594 sensor driftフィールド実験はい承認済み実行中
PR-714 AI triageランダム化はい条件セットアップ
PR-551 message recallサーベイ実験はい承認済み完了
PR-896 heat exposureコホートいいえ保留中草案

Replication R-20

元の効果
0.3 SD
再現の効果
0.3 SD
判定
小さく、同じ符号
公開済み
データとコード付き

テストベッドの空き状況

Protocol and replication board: the screen’s structure, terms and states for Reproducibility and negative results.例示の名称と説明用の値です。設計であり、記録でも稼働中のシステムでもありません。
04In the five domains

Negative results matter in every domain.

Negative results are published in the Labs Evidence series. The National Academies’ report (2019) distinguishes reproducibility from replicability; DORA (2012) supports assessing research on its merits.

  • Negative results.
  • Replication attempts.
05手法とエビデンス

How reproducibility and negative results is modelled, measured and tested.

モデル、その仮定、データ、不確実性を、科学者やエンジニアが確認する形で示します。構造は公表された手法に従っています。描かれた値は例示であり、知見ではありません。

モデル、方程式、仮定

The model structure used for reproducibility and negative results, the assumptions it makes and how each is tested.

要素 i のリスクRi = f(Hi, Ei, Vi, Ci)ハザード、エクスポージャー、脆弱性、対処能力
年間期待損失EAL = ∑k pk · Lk年間確率 pk
結合システムxt+1 = A xt + B ut + εtA carries the couplings, u the shock, ε the error
仮定作られる理由検証の方法
一つの事象の中では、ハザードとエクスポージャーは独立している損失の積分を扱いやすく保つ同時記録に当てはめたコピュラと比較
結合は動作点の近くで線形であるショックを A を通じて伝播させる線形範囲を超えて摂動を与えて比較する
脆弱性曲線は場所を越えて適用できる地域固有の曲線はめったに得られない観測された損失がある場合はそれに照らして検証
入力
来歴付きのバージョン管理されたデータセット
成果物
分布であり、単一の数値ではない
コード
モデルカードと試験とともに公開
再現
同じデータ、コード、環境、シード
標準的なリスクおよび状態空間の定式化です。挙げた前提はこの手法に典型的なもので、審査のために示しており、結果ではありません。
FAIR 原則・GO FAIR と FORCE11W3C PROV・World Wide Web Consortium不確実性の一貫した扱いに関するガイダンス・IPCCCEOS 解析即応データ・地球観測衛星委員会
06指標

何を、どの程度うまく測定しているか。

各指標には、その単位、更新頻度、背後にある出典の種類、値が持つことになるエビデンスのラベルが付いています。値は表示しません:プログラムが自らの権限のもとで値を提供します。

指標単位周期出典の種類ラベル
Computational reproducibilitypercent of sampled studies regenerated from shared code and dataper auditReproducibility audits観測
Replication outcomeproportion of replications meeting the prespecified criterionper programmeCoordinated replication projects観測
Retraction noticescount by field and reason年次Retraction Watch database via Crossref公表統計
Time from concern to correctionか月per caseJournal and integrity office records報告値
Post-retraction citationscitations per retracted article年次Citation data linked to retraction records観測
Null and negative results depositedcount of records年次Repositories and registries報告値
Data available on requestpercent of articles whose data could be obtainedper auditData request audits観測
07出典

エビデンスの出所。

名前の明示された公開データセットと機関の記録。それぞれにライセンス区分があります。合意に基づく出典は、その条件のもとでのみ使用し、再公開することはありません。

出典提供するものライセンス区分
Retraction Watch database (Crossref)Retractions, corrections and expressions of concern with reasonsオープン、帰属表示
Crossref metadata and Crossmark updatesLinks from articles to their corrections and retractionsOpen metadata, no restrictions
OpenAlexWorks, citations, authors and institutions across disciplinesオープン、CC0
FORRT Replication DatabaseReplication attempts and outcomes, mostly in the social and behavioural sciencesオープン、帰属表示
OSF projects of coordinated replication programmesProtocols, data and code of large-scale replicationsOpen, licence per project
PubPeerPost-publication comments identifying possible problems in papersFree access, terms of use
Zenodo (CERN)Citable deposits for null results, data and codeOpen, licence per record
08決定

誰が決め、エビデンスが何に役立つか。

ラボ prepares evidence. The decisions below are taken by the authorities named, under their own rules, and never by the platform.

誰が決定するか質問このページが提供するエビデンス
Journal editors and publishersWhether to correct, retract or issue an expression of concernEvidence of error or misconduct, author response, COPE guidance, reproduction attempts
Research integrity officesWhether an allegation is substantiated and what followsRaw data, records, code, interviews and an independent analysis
研究資金提供者Whether to fund replications and require data and code sharingReproducibility audit results, replication evidence by field, cost of sharing
Guideline developers and systematic reviewersWhether to rely on a study that has been questioned or correctedRetraction and correction status, replication evidence, risk-of-bias assessment

このトピックが生み出す成果物

  • Replication protocols registered before data collection, with success criteria fixed
  • Reproducibility records listing code, data, environment and the outcome of each rerun
  • Deposits of null and negative results with full methods
  • Correction logs that link each notice to the works affected
09中核となる問い

What experts ask about reproducibility.

  • Can an independent team re-run the analysis from the published data and code?
  • Has the finding been replicated with new data, in a new setting or by a different team?
  • Which null or negative results exist, and where are they recorded?
  • When an error is found, how is it corrected and how are users of the result told?
  • Which parts of a workflow, such as software versions or random seeds, could change the answer?
10メカニズムと要因

Why results fail to reproduce.

Many published findings in several disciplines have proved difficult to replicate. The causes are well understood: small samples, flexible analysis, selective reporting, undocumented data processing and incentives that favour novel positive findings. In computational work, results can also depend on software versions, hardware, random seeds and data that change after publication.

Negative results are under-reported because they are harder to publish and seem less interesting. This distorts the evidence base: if only successful trials of an intervention are visible, the intervention looks more effective than it is. Systematic reviews and models built on that evidence inherit the bias.

Corrections matter for the same reason. An error in a widely used dataset or model can propagate into many downstream analyses before it is found.

11手法とデータ

Practices that support reproducibility.

  1. 01

    Open data and code

    Sharing the materials needed to re-run an analysis, within privacy and licensing limits. Some data cannot be shared and must be described instead.

  2. 02

    Computational environments

    Recording software versions and environments, a practice developed with 再現可能なモデリング. Long-term preservation remains hard.

  3. 03

    Registered reports

    Peer review of the protocol before results exist, so publication does not depend on the outcome.

  4. 04

    Correction records

    Dated, visible corrections linked to the original result, rather than silent replacement.

A failed replication does not by itself show the original was wrong; differences in setting, sample or method must be examined before conclusions are drawn.

12手法

どのように研究され、手法が言えないことは何か。

  1. 確率と統計標本サイズと検出力の計画 · バイアス評価を伴うメタ分析ここでの適用
  2. 不確実性の定量化とモデル検証測定の不確かさのバジェット · シミュレーション・モデルの感度分析ここでの適用
  3. 因果推論とインパクト評価ランダム化パイロットと段階的展開 · 準実験的なプログラム評価ここでの適用
  4. 人工知能と機械学習システマティック・レビューのための支援付きスクリーニング · 実験を導く代理モデルここでの適用
13Where this page’s references

Where this page’s references lead.

このページの読解の基準となる機関と文書。状態と版は変わります。各リンクは発行機関へ移動します。

14質問

質問と回答。

What is the difference between reproducibility and replicability?
In the usage of the US National Academies, reproducibility means obtaining the same results from the same data and code, and replicability means obtaining consistent results from new data. Usage varies by field, so definitions should be stated.
Why publish negative results?
They show what did not work, prevent wasted repetition and correct the bias that makes effects look larger than they are. A well-designed study with a null result is a finding.
Does retraction always mean misconduct?
No. Papers are also retracted for honest error, irreproducible results or publisher problems. COPE guidance asks that each notice states the reason.
Can a retracted paper still be cited?
It can be cited as retracted, for example in studies of the literature. Citing it as valid evidence is an error that reviewers and editors should catch.
Will Labs publish a study that found nothing?
Yes. A well-conducted study with a null result is designed to be recorded with the same detail as a positive one.
How do I report an error in a Labs result?
Use the correction routes on the Labs trust pageに送ることができる。受領通知には参照番号と次のステップが示される。
Are corrected results removed?
No. The original stays visible with a dated correction, so anyone who used it can see what changed.
報告書貢献する

このページからエビデンスを提供する。

報告書 is the Consortium’s quarterly publication. What you know about this subject can become evidence, a case or a correction in the next edition, credited to you and published under CC BY 4.0 where it is your own work.

GCRIラボLabs のエビデンス手法と技術
ラボ

手法、データセット、または問いを持ち込んでください。

情報提供と問い合わせは本日から受け付けています。問い合わせには参照番号が付き、次の手順が示されます。申請、支払い、計算資源の割り当て、登録は、担当チーム、規約、審査体制が整ってから開始します。