Risks and capability
Four global risk objects open the portfolio. Order carries no rank. Each is read across driver, exposure, vulnerability, capacity, cascade and consequence; loss metrics are added only where they can be modelled.
Contents
- ·Edition home
- ·Executive summary
- 1Health threats cross every line
- 2Key findings
- 3Systems and sectors at baseline
- 4Risks and capability
- 5High-consequence outbreak that overlaps reduced financing and thin surveillance
- 6Readings from the other desks
- 7The 2027 agenda
- 8Systems in depth
- AMethodology
- BData appendix
- CReferences and record
- ·Complete edition, for print
4.1Risk objects
Each risk is read across the chain from hazard to consequence, with its status and evidence-quality level.
ReportedEQL 4RSK-SR08-HLT-001
Cross-border outbreak without licensed countermeasures
ReportedEQL 4RSK-SR08-HLT-002
Immunity gaps and measles resurgence
- Driver
- 13.5 million zero-dose children and 77% two-dose measles coverage8
- Exposure
- children under five in under-vaccinated areas
- Vulnerability
- routine immunisation disrupted by conflict and financing cuts
- Capacity
- catch-up campaigns; routine services9
- Cascade
- HLT → HLT → FIN
- Horizon
- annual
ReportedEQL 4RSK-SR08-BIO-003
Drug-resistant infection
InferredEQL 3RSK-SR08-BIO-004
Spillover from animals and novel influenza
- Driver
- animal origin of over 60% of emerging diseases; H5 in cattle, with hundreds of human cases reported to WHO over time131848
- Exposure
- farm and slaughter workers, wildlife contact
- Vulnerability
- animal and human surveillance links not bound
- Capacity
- One Health plan of action15
- Cascade
- BIO → HLT → TRD
- Horizon
- 1 to 5 years
4.2Capability ladder
Existence is not readiness. Each of the fifteen capability functions is placed on the ladder by the strongest public evidence at the global level, from a policy listing to performance in real events.
| Function | Rung | Level | Strongest public evidence at baseline |
|---|---|---|---|
| Prevention and mitigation | EXISTS | immunisation and food-safety programmes; coverage uneven89 | |
| Monitoring and observation | ADEQUATE | WHO and regional agencies publish notices; 48% of countries did not report resistance data6 | |
| Early warning | EXISTS | IHR alert levels, now including a pandemic emergency tier4 | |
| Preparedness and planning | EXISTS | national IHR authorities required by the amendments4 | |
| Redundancy and reserves | LISTED | stockpiles and surge capacity not consolidated | |
| Response | DEMONSTRATED | the mpox emergency ended after sustained decline; a 2025 Ebola outbreak ended523 | |
| Continuity of critical services | LISTED | routine services during outbreaks not consolidated | |
| Recovery | LISTED | post-outbreak recovery data not consolidated | |
| Adaptation | EXISTS | One Health joint plan of action for 2022 to 202615 | |
| Social protection | LISTED | support for affected households not consolidated | |
| Finance and insurance | LISTED | pooled financing exists; amounts not verified here3122 | |
| Institutional coordination | EXISTS | IHR, Quadripartite and the Pandemic Agreement process4133 | |
| Technical infrastructure | EXISTS | laboratory and surveillance networks; high-containment laboratory oversight not bound3342 | |
| Workforce | LISTED | health and veterinary workforce not consolidated | |
| Research capacity | ADEQUATE | candidate vaccines in trials for Bundibugyo virus47 | |
| A capability listed in policy is not a tested one; each rung is the strongest public evidence at baseline. | |||
Notes
Numbers are the edition’s reference numbers, so a note reads the same in every chapter. The full list, with every source and its licence, is in Annex C. Annex C, references
- 47ECDC (ed.), Ebola disease outbreak caused by Bundibugyo virus, Democratic Republic of the Congo, update of 30 September 2026 (cases up to 27 September 2026: 8,116 confirmed and 3,924 deaths; seven provinces; 63 of 167 health zones; Uganda 20 confirmed cases). European Centre for Disease Prevention and Control, Stockholm. Observation year 2026. Accessed 2026-11-03.back
- 8WHO (ed.), Immunisation coverage, fact sheet (WUENIC estimates for 2025, released 15 July 2026). World Health Organization, Geneva. Observation year 2025. Accessed 2026-11-03.back
- 9WHO (ed.), Measles, fact sheet (95,000 deaths in 2024; coverage in 2025; page dated 15 July 2026). World Health Organization, Geneva. Observation year 2024. Accessed 2026-11-03.back
- 6WHO (ed.), WHO warns of widespread resistance to common antibiotics worldwide, news release of 13 October 2025 on the Global antibiotic resistance surveillance report 2025 (data year 2023; 104 reporting countries). World Health Organization, Geneva. Observation year 2023. Accessed 2026-11-03.back
- 7WHO (ed.), Antimicrobial resistance, fact sheet (more than 4.7 million deaths associated with bacterial resistance in 2021; 10% reduction target by 2030). World Health Organization, Geneva. Observation year 2021. Accessed 2026-11-03.back
- 13WHO (ed.), One Health, fact sheet (Quadripartite; over 60% of emerging infectious diseases reported globally come from animals). World Health Organization, Geneva. Observation year 2025. Accessed 2026-11-03.back
- 18WHO (ed.), Influenza (avian and other zoonotic), fact sheet of 21 January 2026 (hundreds of human cases; no cumulative count on the page). World Health Organization, Geneva. Observation year 2026. Accessed 2026-11-03.back
- 48FAO, WHO and WOAH (eds.), Updated joint FAO/WHO/WOAH public health assessment of recent high pathogenicity avian influenza A(H5) virus events in animals and people, 18 May 2026 (since 2024 and as of 1 March 2026, 1,088 dairy herds in 19 US states affected; human detections reported in Bangladesh, Mexico and the United States). Food and Agriculture Organization, World Health Organization and World Organisation for Animal Health, Rome, Geneva and Paris. Observation year 2026. Accessed 2026-11-03.back
- 15WHO, FAO, UNEP and WOAH (eds.), One Health Joint Plan of Action launched to address health threats to humans, animals, plants and environment, news release of 17 October 2022 (plan period 2022 to 2026; six action tracks). World Health Organization, Geneva. Observation year 2022. Accessed 2026-11-03.back
- 4WHO (ed.), Amended International Health Regulations enter into force, news release of 19 September 2025 (11 of 196 States Parties rejected; pandemic emergency level; National IHR Authorities). World Health Organization, Geneva. Observation year 2025. Accessed 2026-11-03.back
- 5WHO (ed.), Fifth meeting of the International Health Regulations (2005) Emergency Committee regarding the upsurge of mpox 2024, statement published 30 October 2025 (Director-General determination of 5 September 2025). World Health Organization, Geneva. Observation year 2025. Accessed 2026-11-03.back
- 23STAT (ed.), Congo’s last Ebola patient is discharged, article of 20 October 2025 (Kasai province outbreak declared 4 September 2025; 64 cases, 43 deaths; 42-day countdown). STAT, Boston. Observation year 2025. Accessed 2026-11-03.back
- 31UNVERIFIED, not opened: The Pandemic Fund (ed.), funding rounds and projects (US$499.6 million to 20 projects in the third round, February 2026; US$1.4 billion across three rounds), taken from search-result summaries; the site returned an access error. World Bank and WHO, Washington and Geneva. Observation year 2026. Accessed 2026-11-03.back
- 22IHME (ed.), Financing Global Health 2025, news release of 15 July 2025 (development assistance for health USD 39 billion in 2025; USD 80 billion peak in 2021; US financing down 67%), read through a syndicated release. Institute for Health Metrics and Evaluation, Seattle. Observation year 2025. Accessed 2026-11-03.back
- 3WHO (ed.), Seventy-ninth World Health Assembly daily update, 19 May 2026 (decision to continue the annex negotiations; outcome to the Eightieth Assembly in May 2027 or a special session in 2026). World Health Organization, Geneva. Observation year 2026. Accessed 2026-11-03.back
- 33UNVERIFIED, not opened: King’s College London and George Mason University, Global BioLabs Report 2023 (51 operating level-4 laboratories in 27 countries and 18 planned or under construction), taken from search-result summaries; the document text was not readable. Observation year 2023. Accessed 2026-11-03.back
- 42UNVERIFIED, not opened: WHO, Laboratory biosafety manual, fourth edition. World Health Organization, Geneva, 2020, cited from memory. Observation year 2020. Accessed 2026-11-03.back
