Systems and sectors at baseline
Contents
- ·Edition home
- ·Executive summary
- 1Health threats cross every line
- 2Key findings
- 3Systems and sectors at baseline
- 4Risks and capability
- 5High-consequence outbreak that overlaps reduced financing and thin surveillance
- 6Readings from the other desks
- 7The 2027 agenda
- 8Systems in depth
- AMethodology
- BData appendix
- CReferences and record
- ·Complete edition, for print
3.1Where each system stood at evidence close
HLT · Outbreak
Confirmed Ebola Bundibugyo cases, DRC
8,116to 27 September 2026; 3,924 deaths.
Reported2026ECDC47
HLT · Rules
States Parties rejecting the 2024 IHR amendments
11of 196in force from 19 September 2025.
Reported2025WHO4
HLT · Immunity
Zero-dose children
13.5milliontwo-dose measles coverage 77%.
Reported2025WHO8
BIO · Resistance
Bacterial infections resistant to treatment
1 in 6laboratory-confirmed infections.
Reported2023WHO6
FIN · Financing
Development assistance for health
39USD billion51% below the 2021 peak.
Reported2025IHME22
SYS · Treaty
Pandemic Agreement annex, next decision point
May 2027or a special session in 2026.
Reported2026WHO3
3.2Domain posture
Each of the twelve coupled domains is read through health security, in words, not scored. The coupling column names the dependency that carries health security risk into each domain.
| Domain | Posture at baseline | Coupling | Status |
|---|---|---|---|
| WAT | Cholera killed 7,870 people in 47 reporting countries in 2025; water and sanitation failure carries disease. | WAT → HLT | Reported EQL 4 |
| ENE | Health facilities and cold chains depend on power; no consolidated series here. | ENE → HLT | Inferred EQL 2 |
| FOO | Food safety and nutrition shape outcomes; no consolidated series here. | FOO → HLT | Expert input EQL 2 |
| HLT | The core system: 8,116 confirmed Ebola cases in the DRC; 13.5 million zero-dose children. | the core system | Reported EQL 4 |
| BIO | Over 60% of emerging infectious diseases reported globally come from animals. | BIO → HLT | Reported EQL 3 |
| CLI | Dengue reached 14.6 million cases in 2024; the link to climate is not read here. | CLI → HLT | Inferred EQL 2 |
| INF | Laboratories, transport and communications carry samples and supplies; no consolidated series here. | INF ↔ HLT | Inferred EQL 2 |
| FIN | Aid for health fell to USD 39 billion in 2025; TB needs USD 22 billion a year. | FIN → HLT | Reported EQL 3 |
| DAT | 48% of countries did not report resistance data in 2023; incident data are not on a common basis. | DAT ↔ HLT | Reported EQL 4 |
| AIC | Computational tools for surveillance and design of biological agents; not read in this edition. | AIC → HLT | Expert input EQL 2 |
| MIN | Medical supply chains depend on minerals and materials; chokepoint data sit in sibling editions. | MIN → HLT | Inferred EQL 2 |
| TRD | WHO advised against travel and trade restrictions during the 2026 Ebola outbreak. | HLT ↔ TRD | Reported EQL 3 |
3.3Sector screens
All sixteen sectors are screened for their dependence on health security, on the same grammar as every national edition. The evidence column describes coverage of the baseline evidence, not the performance of the sector.
| Code | Sector | Baseline evidence | Exposure to watch | Evidence coverage |
|---|---|---|---|---|
| GS-00 | Cross-system | health threats cross people, animals and borders1347 | outbreak with thin financing | PARTIAL |
| GS-01 | Water | cholera deaths highest since 199910 | sanitation failure | PARTIAL |
| GS-02 | Energy | facilities and cold chains depend on power | outage during outbreak | THIN |
| GS-03 | Food and agrifood | food safety and animal disease | zoonotic spillover | THIN |
| GS-04 | Health | Ebola, mpox, measles, resistance47596 | concurrent emergencies | GOOD |
| GS-05 | Finance and economy | aid for health USD 39 billion22 | financing shock | PARTIAL |
| GS-06 | Development | zero-dose children 13.5 million8 | weak routine immunisation | GOOD |
| GS-07 | Climate | dengue 14.6 million cases in 202411 | vector range | THIN |
| GS-08 | Disaster | outbreaks as compound disasters16 | concurrent hazards | PARTIAL |
| GS-09 | Infrastructure | transport and laboratories link outbreak zones | access and sample transport | THIN |
| GS-10 | Cities | Kampala cases in 202626 | urban spread | THIN |
| GS-11 | Biodiversity | animal origin of over 60% of emerging diseases13 | habitat and wildlife contact | PARTIAL |
| GS-12 | Earth observation | environmental data for spillover risk | data links | THIN |
| GS-13 | Cyber and digital | resistance data missing for 48% of countries6 | surveillance data gaps | PARTIAL |
| GS-14 | Policy | IHR amendments and Pandemic Agreement annex43 | ratification and compliance | GOOD |
| GS-15 | Science | spillover and emergence science is mature394041 | data at operating scale | PARTIAL |
Notes
Numbers are the edition’s reference numbers, so a note reads the same in every chapter. The full list, with every source and its licence, is in Annex C. Annex C, references
- 47ECDC (ed.), Ebola disease outbreak caused by Bundibugyo virus, Democratic Republic of the Congo, update of 30 September 2026 (cases up to 27 September 2026: 8,116 confirmed and 3,924 deaths; seven provinces; 63 of 167 health zones; Uganda 20 confirmed cases). European Centre for Disease Prevention and Control, Stockholm. Observation year 2026. Accessed 2026-11-03.back
- 4WHO (ed.), Amended International Health Regulations enter into force, news release of 19 September 2025 (11 of 196 States Parties rejected; pandemic emergency level; National IHR Authorities). World Health Organization, Geneva. Observation year 2025. Accessed 2026-11-03.back
- 8WHO (ed.), Immunisation coverage, fact sheet (WUENIC estimates for 2025, released 15 July 2026). World Health Organization, Geneva. Observation year 2025. Accessed 2026-11-03.back
- 6WHO (ed.), WHO warns of widespread resistance to common antibiotics worldwide, news release of 13 October 2025 on the Global antibiotic resistance surveillance report 2025 (data year 2023; 104 reporting countries). World Health Organization, Geneva. Observation year 2023. Accessed 2026-11-03.back
- 22IHME (ed.), Financing Global Health 2025, news release of 15 July 2025 (development assistance for health USD 39 billion in 2025; USD 80 billion peak in 2021; US financing down 67%), read through a syndicated release. Institute for Health Metrics and Evaluation, Seattle. Observation year 2025. Accessed 2026-11-03.back
- 3WHO (ed.), Seventy-ninth World Health Assembly daily update, 19 May 2026 (decision to continue the annex negotiations; outcome to the Eightieth Assembly in May 2027 or a special session in 2026). World Health Organization, Geneva. Observation year 2026. Accessed 2026-11-03.back
- 13WHO (ed.), One Health, fact sheet (Quadripartite; over 60% of emerging infectious diseases reported globally come from animals). World Health Organization, Geneva. Observation year 2025. Accessed 2026-11-03.back
- 10WHO (ed.), Cholera, fact sheet (451,499 cases and 7,870 deaths reported from 47 countries in 2025). World Health Organization, Geneva. Observation year 2025. Accessed 2026-11-03.back
- 5WHO (ed.), Fifth meeting of the International Health Regulations (2005) Emergency Committee regarding the upsurge of mpox 2024, statement published 30 October 2025 (Director-General determination of 5 September 2025). World Health Organization, Geneva. Observation year 2025. Accessed 2026-11-03.back
- 9WHO (ed.), Measles, fact sheet (95,000 deaths in 2024; coverage in 2025; page dated 15 July 2026). World Health Organization, Geneva. Observation year 2024. Accessed 2026-11-03.back
- 11WHO (ed.), Dengue and severe dengue, fact sheet of 21 August 2025 (more than 14.6 million cases in 2024). World Health Organization, Geneva. Observation year 2024. Accessed 2026-11-03.back
- 16Global Preparedness Monitoring Board (ed.), A World on the Edge: Priorities for a Pandemic-Resilient Future, 2026 report (reports page read; six emergencies of international concern in the past decade). GPMB, Geneva. Observation year 2026. Accessed 2026-11-03.back
- 26WHO (ed.), Disease Outbreak News 2026-DON612, 3 July 2026 (1,481 confirmed cases and 454 deaths; one imported case in France). World Health Organization, Geneva. Observation year 2026. Accessed 2026-11-03.back
- 39UNVERIFIED, not opened: Jones, K.E. et al., Global trends in emerging infectious diseases, Nature 451, 990 to 993, 2008, cited from memory. Springer Nature. Observation year 2008. Accessed 2026-11-03.back
- 40UNVERIFIED, not opened: Allen, T. et al., Global hotspots and correlates of emerging zoonotic diseases, Nature Communications 8, 1124, 2017, cited from memory. Springer Nature. Observation year 2017. Accessed 2026-11-03.back
- 41UNVERIFIED, not opened: Carlson, C.J. et al., Climate change increases cross-species viral transmission risk, Nature 607, 555 to 562, 2022, cited from memory. Springer Nature. Observation year 2022. Accessed 2026-11-03.back
