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GCRI · 生物技术与生物安全

两用与伦理

Much life sciences research is dual use: knowledge, materials and technologies developed for beneficial purposes could also be misused to cause harm. This topic, studied at Biotechnology and Biosecurity, a platform of The Global Centre for Risk and Innovation (GCRI), examines how research of concern is identified, how responsibility is shared between researchers, institutions, funders and publishers, and how concerns are escalated, alongside the wider ethical questions biotechnology raises.

02核心问题

专家提出的问题。

  • How can research of concern be identified early, without discouraging beneficial science?
  • What responsibilities do researchers, institutions, funders and publishers each hold?
  • How should concerns be raised and escalated, and how are those who raise them protected?
  • How should the publication of sensitive findings be handled?
  • How do ethical questions of consent, equity and benefit sharing apply to biotechnology?
03监测

监督与能力登记册。

团队跟踪该主题时会使用的界面:其指标、状态与决策。名称为示例,数值仅作示意。

监督与能力登记册

Dual use and ethics · National committee · Review year 2

  • 设有委员会的机构,%
    61关注
  • 已培训员工,%
    64正常
  • 已完成审查
    55今年
  • 已提交的事件报告
    13信息
仅限能力建设与监督GCRI · 生物技术与生物安全

机构监督

A 机构活跃Q487当前
研究园区活跃Q482审计到期
生物制造场所组建中无46支持
诊断网络活跃Q381当前

范围说明

涵盖
治理、培训、审查能力
不包括
技术方法与智能体
权限
国家监督机构
标签
SURVEY
Oversight and capacity register: the screen’s structure, terms and states for Dual use and ethics.示例名称和示意数值;是设计方案,并非记录或实时系统。
04跨领域

Dual-use governance applies wherever life-science research touches the domains.

Governance analyses are designed for the 指数级技术系列. The WHO framework (2022) and the Biological Weapons Convention set the frame; GCRI publishes governance analysis, never methods of concern.

  • Governance comparisons.
  • Ethics review lessons.
05方法与证据

How dual use and ethics is modelled, measured and tested.

模型、其假设、数据和不确定性,以科学家或工程师会核查的形式呈现。结构遵循已发表的方法。所取数值仅为示意,不是研究发现。

不确定性区间

How far the outlook for dual use and ethics could spread, shown as ranges rather than a single line.

现在+5+10+15+20+25+30 y高低很可能区间可能区间
中心估计值
集合的中位数
范围
IPCC 校准用语中的“可能”和“很可能”
集合
明示成员、情景和初始条件
配合阅读
结果对每项输入的敏感性
示意性的指数尺度集合离散度;形式遵循 IPCC 不确定性指南。并非预测。
FAIR 指导原则 · GO FAIR 和 FORCE11W3C PROV · 万维网联盟关于一致处理不确定性的指南 · IPCCCEOS 分析就绪数据 · 地球观测卫星委员会
06机制

驱动因素与动态。

Dual-use concerns arise because the same experiments that reveal how biological 系统 work can, in rare cases, produce knowledge or materials that could be misused. Policies in several countries define categories of research that require additional review, and funders and journals have developed processes for assessing sensitive work. These processes depend heavily on the judgement and awareness of researchers themselves.

Ethics in biotechnology extends beyond misuse: consent for the use of genetic data, equitable access to benefits, fair sharing of benefits from genetic resources, and respect for communities and ecosystems. A culture of responsibility, in which researchers consider consequences and feel able to raise concerns, is widely regarded as the foundation of effective governance. The platform works at the level of governance, evaluation and risk methods. It publishes no protocols, techniques or information that would increase anyone’s capacity to cause harm.

07方法与局限

How it is studied.

  1. 01

    Policy analysis

    Comparative studies of dual-use review policies, funder conditions and publication practices.

  2. 02

    Ethics frameworks

    Structured approaches for weighing benefits, risks and responsibilities in research decisions.

  3. 03

    Education research

    Studies of how training and culture influence awareness and reporting.

  4. 04

    局限

    Misuse potential is hard to judge in advance, review processes vary in rigour, and discussions of risk must avoid creating the hazards they seek to prevent.

08决定

What it informs and who decides.

This evidence informs institutional review processes, funder and publisher policies, training and national oversight frameworks. Researchers, institutional review committees, funders, publishers and regulators decide within their roles. Governance dialogue is convened by 全球风险论坛(Global Risks Forum,GRF)的卫生与生物安全治理. Concerns can be raised through 更正与关切. Related topics are 实验室生物安全与生物安保, synthetic biology and biological threats; methods sit on molecular and life sciences.

Published analysis on this topic is designed to carry a named subject reviewer, its references and the views of independent specialists, including biosafety professionals and those who disagree.

09来源

Where this page’s references lead.

阅读本页时所对照的机构和文件。状态和版本会变化;每个链接都指向发布机构。

10问题

问题与解答。

Does dual use mean research should stop?
No. Most research has great benefit. The aim is to identify the small share that needs additional care and to manage it responsibly.
Who is responsible for identifying research of concern?
Responsibility is shared: researchers first, then institutions, funders, publishers and regulators.
How can I raise a concern about research?
Through your institution’s procedures, or write to 诚信关切表单来信。确认回执提供参考编号并说明下一步。
由谁审查该主题的覆盖范围?
Published analysis is designed to be reviewed by a named subject reviewer with relevant expertise, to cite its references and to include independent specialist voices. Where specialists disagree, the disagreement is reported rather than resolved by omission.
报告贡献

从本页贡献证据。

报告 is the Consortium’s quarterly publication. What you know about this subject can become evidence, a case or a correction in the next edition, credited to you and published under CC BY 4.0 where it is your own work.

GCRI生物技术与生物安全指数级技术证据简报
生物技术与生物安全

带来一种方法、一个数据集或一个问题。

信息和咨询现已开放。每项咨询都会获得一个编号,并告知下一步;申请、付款、算力分配和注册只有在相应团队、条款和审查能力就绪时才会开放。