Indigenous Knowledge Programs empower communities and leaders to address Water-Energy-Food (WEF) nexus challenges by integrating traditional knowledge with modern sustainability solutions. Key initiatives include the Indigenous Innovators Program, Community Resilience Builders, Knowledge Keepers Fellowship, Impact Accelerator, and Collaborative Wisdom Labs. These programs provide incubation support, mentorship, funding, and specialized training, fostering projects that enhance disaster risk reduction and sustainable development. Annual hackathons and a final demo day showcase solutions, attract investors, and build cross-sector partnerships. By combining indigenous wisdom with innovative approaches, Nexus Accelerator drives systemic change, builds community resilience, and supports sustainable development for a sustainable and equitable future